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Screening for catecholamine-secreting tumors in children when
accompanied by homovanillic acid (HVA)
Supporting a diagnosis of neuroblastoma
Monitoring neuroblastoma treatment
In the past, this test has been used to screen for pheochrome-
cytoma. However, VMA is not the analyte of choice to rule out a
diagnosis of pheochromocytoma. Recommended tests for this
purpose are #81609 "Metanephrines, Fractionated, Free, Plasmaâ€
(p. 540), #83006 "Metanephrines, Fractionated, 24-Hour, Urineâ€
(p. 541), and #9276 "Catecholamine Fractionation, Urinary, Freeâ€
(p. 155).
Liquid Chromatography-Tandem Mass Spectrometry
(LC-MS/MS) Stable Isotope Dilution Analysis
For children 14 years of age and younger, #9254
"Vanillylmandelic Acid (VMA) and Homovanillic Acid,
(HVA), Pediatric, Urine" is the recommended test.
Vanillylmandelic Acid (VMA), U
VMA
3-methoxy-4-hydroxymandelic acid
4-hydroxy-3-methoxymandelic acid
Neuroblastoma Profile (See Q & A Section of MayoAccess)
Vanilmandelic acid
VMA, Urine

