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Test ID: AGIDE    
Autoimmune Gastrointestinal Dysmotility Evaluation, Serum

Secondary ID A test code used for billing and in test definitions created prior to November 2011

89886

NY State Approved Indicates the status of NY State approval and if the test is orderable for NY State clients.

Yes

Useful For Suggests clinical disorders or settings where the test may be helpful

Investigating unexplained weight loss, early satiety, anorexia, nausea, vomiting, constipation or diarrhea in a patient with past or family history of cancer or autoimmunity

 

Directing a focused search for cancer

 

Investigating gastrointestinal symptoms that appear in the course or wake of cancer therapy, not explainable by recurrent cancer, metastasis or therapy; detection of autoantibodies on this profile helps differentiate autoimmune gastrointestinal dysmotility from the effects of chemotherapy

 

Detecting early evidence of cancer recurrence in previously seropositive patients who have a rising titer of 1 or more autoantibodies

Profile Information A profile is a group of laboratory tests that are ordered and performed together under a single Mayo Test ID. Profile information lists the test performed, inclusive of the test fee, when a profile is ordered and includes reporting names and individual availability.

Test IDReporting NameAvailable SeparatelyAlways Performed
PAINTInterpretive CommentsNoYes
ANN1SAnti-Neuronal Nuclear Ab, Type 1NoYes
STRStriational (Striated Muscle) Ab, SYesYes
CCNN-Type Calcium Channel AbNoYes
ARBIACh Receptor (Muscle) Binding AbYesYes
GANGAChR Ganglionic Neuronal Ab, SNoYes
VGKCNeuronal (V-G) K+ Channel Ab, SNoYes
GD65SGAD65 Ab Assay, SYesYes

Reflex Tests Lists test(s) that may or may not be performed, at an additional charge, depending on the result and interpretation of the initial test(s)

Test IDReporting NameAvailable SeparatelyAlways Performed
WBNParaneoplastic Autoantibody WBlot,SNoNo
CRMWSCRMP-5-IgG Western Blot, SNoNo
ARMOACh Receptor (Muscle) Modulating AbNoNo
ABLOTAmphiphysin Western Blot, SNoNo
NMDCSNMDA-R Ab CBA, SNoNo
AMPCSAMPA-R Ab CBA, SNoNo
GABCSGABA-B-R Ab CBA, SNoNo
NMDISNMDA-R Ab IF Titer Assay, SNoNo
AMPISAMPA-R Ab IF Titer Assay, SNoNo
GABISGABA-B-R Ab IF Titer Assay, SNoNo
ANN2SAnti-Neuronal Nuclear Ab, Type 2NoNo
ANN3SAnti-Neuronal Nuclear Ab, Type 3NoNo
PCABPPurkinje Cell Cytoplasmic Ab Type 1NoNo
PCAB2Purkinje Cell Cytoplasmic Ab Type 2NoNo
PCATRPurkinje Cell Cytoplasmic Ab Type TrNoNo
CRMSCRMP-5-IgG, SNoNo
AMPHSAmphiphysin Ab, SNoNo
AGN1SAnti-Glial Nuclear Ab, Type 1NoNo
NMOCSNMO/AQP4-IgG CBA, SYesNo

Testing Algorithm Delineates situation(s) when tests are added to the initial order. This includes reflex and additional tests.

If indirect immunofluorescence assay (IFA) (ANN1S) pattern is indeterminate, then WBN is performed at an additional charge.

If IFA pattern suggests CRMP-5-IgG, then CRMS and/or CRMWS are performed at an additional charge.

If IFA pattern suggests amphiphysin antibody, then AMPHS and/or ABLOT are performed at an additional charge.

If IFA (ANN1S) pattern suggests antineuronal nuclear antibody, type 2; antineuronal nuclear antibody, type 3; Purkinje cell cytoplasmic antibody, type 1; Purkinje cell cytoplasmic antibody, type 2; Purkinje cell cytoplasmic antibody, type Tr; and/or anti-glial nuclear antibody, type 1; then ANN2S, ANN3S, PCABP, PCAB2, PCATR, and/or AGN1S are performed at an additional charge.

If IFA pattern suggests NMO/AQP4-IgG, then NMOCS is performed at an additional charge.

If IFA pattern suggests NMDA-R, then NMDCS and/or NMDIS are performed at an additional charge.

If IFA pattern suggests AMPA-R, then AMPCS and/or AMPIS are performed at an additional charge.

If IFA pattern suggests GABA-B-R, then GABCS and/or GABIS are performed at an additional charge.

If ACh receptor binding antibody is >0.02, then ARMO and CRMWS are performed at an additional charge.

 

See Autoimmune Gastrointestinal Dysmotility Evaluation Testing Algorithm in Special Instructions.

Special Instructions and Forms Describes specimen collection and preparation information, test algorithms, and other information pertinent to test. Also includes pertinent information and consent forms to be used when requesting a particular test

Method Name A short description of the method used to perform the test

ANN1S, ANN2S, ANN3S, PCABP, PCAB2, PCATR, AMPHS, CRMS, AGN1S, AMPIS, NMDIS, GABIS: Indirect Immunofluorescence Assay (IFA)

STR: Enzyme Immunoassay (EIA)

CCN, GD65S, ARBI, ARMO, GANG, VGKC: Radioimmunoassay (RIA)

WBN, CRMWS, ABLOT: Western Blot

NMDCS, AMPCS, GABCS: Cell-Binding Assay (CBA)

Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name

Autoimmune GI Dysmotility Eval, S

Aliases Lists additional common names for a test, as an aid in searching

AChR (Acetylcholine Receptor)
ANNA (Antineuronal Nuclear Antibody)
Anti-CV2
Anti-Enteric Neuronal Antibody
Anti-GAD65 (Anti-Glutamic Acid Decarboxylase)
Anti-Hu
Anti-Skeletal Muscle Antibodies
Antineuronal
Calcium Channel Blockers
Cerebellar Antibodies
Chorea
Collapsin Response-Mediator Protein-5 Antibody (CRMP-5), Serum
CRMP-5, IgG
Dorsal Root Ganglion Antibody
Glutamate Decarboxylase Antibodies (GAD65)
Hu Antibody
Motor End-Plate Antibody
Motor Nerve Terminal Antibodies
Muscle (Skeletal) Antibodies
Muscle Culture Antibodies
Myoid Antibody
N-Type Calcium Channel Antibody
Neuromyotonia
Neuronal Nuclear Antibody Panel
Neuronal Potassium Channel Ab
Neuronal-Anti
P/Q Type Calcium Channel Antibody
Paraneoplastic Antibodies
Paraneoplastic Autoantibody Evaluation
Paraneoplastic Neurological Autoimmunity
Potassium Channel Antibodies (specify)
Stiff-man Syndrome
Striational (Striated Muscle) Antibodies
VGCC (Voltage-Gated Calcium Channel) Antibodies
VGKC
VGPC
Voltage-Gated Potassium Channel Ab
Acetylcholine Receptor (Muscle AChR) Antibodies
Cantoxin (Receptor Antibodies)
Cramp-Fasciculation
Isaacs Disease
Neuromuscular Hyperexcitability
Neuronal Ganglionic Acetylcholine Receptor Antibody