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Unit Code 89319:
T-Cell Subsets, Naive, Memory and Activated

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Useful For

Determining the presence of naive, memory, and activated T cells

in various clinical contexts including autoimmune diseases,

immunodeficiency states, T-cell recovery posthematopoietic

stem cell transplant, DiGeorge syndrome, and as a measure

for T-cell immune competence 

 

Naive T cells results can be used a surrogate marker for thymic-derived

T-cell reconstitution, when used in conjunction with assessment of

T-cell receptor excision circles (#87959 "T-Cell Receptor Excision

Circles [TREC] Analysis for Immune Reconstitution")

 

Assessing a patient's relative risk for infections

 

Evaluation of patients with cellular or combined primary

immunodeficiencies

 

Evaluation of T-cell reconstitution after hematopoietic

stem cell transplant, chemotherapy, biological therapy,

immunosuppression or immunomodulator therapy

 

Evaluation of patients with autoimmune diseases

 

Evaluation of HIV-positive patients for naive and memory subsets

 

Evaluation of T-cell immune competence (presence of memory and

activated T cells) in patients with recurrent infections

Method Name

Flow Cytometry

Reporting Name

T Cell Phenotyping, Advanced

Ordering Mnemonic

TCP

Aliases

Activated T-cells

Activated T-Cells

CD27 T-cells

CD28 T-cells

CD4 T-cells

CD62L T-cells

CD8 T-cells

Central memory T-cells

DiGeorge syndrome T-cells

Effector memory T-cells

HIV T-cells

Immune competence T-cells

Immune reconstitution T-cells

Infection T-cells

Intestinal lymphangiectasia T-cells

Memory

MHC class II-positive T-cells

Naive

T-cell depletion T-cells


Key