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Unit Code 89199:
Celiac Disease Serology Cascade

Useful For Suggests clinical disorders or settings where the test may be helpful

Evaluating patients suspected of having celiac disease, including

patients with compatible symptoms, patients with atypical

symptoms, and individuals at increased risk (family history,

previous diagnosis with associated disease, positivity for DQ2

and/or DQ8)

Profile Information A profile is a group of laboratory tests that are ordered and performed together under a single Unit Code. Profile information lists tests performed, inclusive of the test fee, when a profile is ordered and includes reporting names and individual availability.

 Unit Code  Reporting Name  Available Separately  Always Performed 
 29033  Immunoglobulin A (IgA), S Yes (Order #8157)Yes
 29458  Celiac Disease Interpretation No Yes

Reflex Tests Lists test(s) that may or may not be performed, at an additional charge, depending on the result and interpretation of the initial test(s)

 Unit Code  Reporting Name  Available Separately  Always Performed 
82587 Tissue Transglutaminase Ab, IgA, S Yes No
9360 Endomysial Abs, S (IgA) Yes No
89029 Gliadin(Deamidated) Ab, IgA, S Yes No
83660 Tissue Transglutaminase Ab, IgG, S Yes No
89030 Gliadin(Deamidated) Ab, IgG, S Yes No

Testing Algorithm Delineates situation(s) when tests are added to the initial order. This includes reflex and additional tests.

If IgA is age-specified normal, then tissue transglutaminase (tTG) IgA will be performed at an additional charge.

If tTG IgA is equivocal, then endomysial antibodies IgA and deaminated gliadin antibody IgA will be performed at an additional charge.

If IgA is > or =1.0 mg/dL but lower than age-specified normal, then tTG IgA, tTG IgG, deaminated gliadin IgA, and deaminated gliadin IgG will be performed at an additional charge.

If IgA is below detection (<1.0 mg/dL), then tTG IgG and deaminated gliadin IgG will be performed at an additional charge.

Special Instructions and Forms Describes specimen collection and preparation information, test algorithms, and other information pertinent to test. Also includes pertinent information and consent forms to be used when requesting a particular test

• Celiac Disease Diagnostic Testing Algorithm 
• Celiac Disease Comprehensive Cascade 
• Celiac Disease Comprehensive Cascade for Patients on a Gluten-Free Diet 
• Celiac Disease Routine Treatment Monitoring Algorithm 
• Celiac Disease Serology Cascade 

Method Name A short description of the method used to perform the test

29033: Nephelometry

82587, 83660, 89029, 89030: Enzyme-linked Immunosorbent Assay (ELISA)

9360: Indirect immunofluorescence assay (IFA)

See "Celiac Disease Diagnostic Testing Algorithm", "Celiac Disease Comprehensive Cascade", "Celiac Disease Comprehensive Cascade for Patients on a Gluten-Free Diet", "Celiac Disease Routine Treatment Monitoring Algorithm", and "Celiac Disease Serology Cascade" in Special Instructions.

Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name

Celiac Disease Serology Cascade

Ordering Mnemonic An alternate Mayo code (to the Unit Code) for a test

CDSP

Aliases Lists additional common names for a test, as an aid in searching

Anti-Endomysial Antibody

Antiendomysial Antibody

Antimesothelial Antibody

Celiac Disease

Coeliac Disease

Dermatitis Herpetiformis

EA

EMA

Failure to Thrive

Gamma-Globulins, Quantitative

Gliadin Antibodies IgA

Gliadin Antibodies IgG

Gliadin IgA, Serum

Gliadin IgG, Serum

Gluten-sensitive Enteropathy

IgA (Immunoglobulin A)

Immunofluorescence Antibodies

Malabsorption

Soft-CDSP

Sprue

Tissue Transglutaminase Ab IgA

Transglutaminase(tTG)

tTG