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Unit Code 8905:
Orotic Acid, Urine

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Useful For

Evaluation of the differential diagnosis of hyperammonemia

and hereditary orotic aciduria.

 

When orotic acid is measured after a protein load or allopurinol

administration, excretion of orotic acid is a very sensitive

indicator of ornithine transcarbamylase (OTC) activity.  The

allopurinol test can be used to determine whether a female is

heterozygous for X-linked OTC deficiency when an OTC deficient

patient has been identified in her family.

Method Name

Colorimetric

Reporting Name

Orotic Acid, U

Ordering Mnemonic

OROT

Key