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Unit Code 89041:
T-Cell Lymphoma, FISH, Tissue

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Useful For

Detecting a neoplastic clone associated with the common

chromosome abnormalities seen in patients with various

T-cell lymphomas

 

Tracking known chromosome abnormalities and response to

therapy in patients with T-cell neoplasms

Reflex Tests

 Unit Code  Reporting Name  Available Separately  Always Performed 
80024 One Additional FISH Probe No No
80025 Two Additional FISH Probes No No
87825 Three Additional FISH Probes No No
80026 Four Additional FISH Probes No No
87826 Five Additional FISH Probes No No
87827 Six Additional FISH Probes No No
87828 Seven Additional FISH Probes No No
87829 Eight Additional FISH Probes No No
87830 Nine Additional FISH Probes No No
87831 Ten Additional FISH Probes No No
87832 Eleven Additional FISH Probes No No
87833 Twelve Additional FISH Probes No No

Testing Algorithm

This test includes a mini-pathology consultation to evaluate appropriate

FISH probes and translocations to investigate. Panel includes testing

for the following anomalies via the probes listed:

 

t(14;var)(q32.1;var), TCL1

-7/7q-/i(7q), D7S486/Cen7

8, Cen 8/c-MYC

t(2;var)(p23.2;var)/inv(2), ALK

ABL/CAN co-amplification, ABL/CAN/Cen9

Del(9)(p21), p16/Cen9

T(911;var)(q23;var), MLL

 

If the patient is being tracked for known anomalies, please indicate

which anomalies need to be investigated.

 

When this test is ordered, 2 FISH probes are included. If further

probes are needed, they will be added at an additional charge.

Special Instructions and Forms

• Informed Consent Form for DNA Testing 
• Cytogenetics Hematologic FISH Panel Patient Information Sheet 

Method Name

Fluorescence In Situ Hybridization (FISH) with DNA Probes

Reporting Name

T-Cell Lymphoma, FISH, Ts

Ordering Mnemonic

PFTLYM

Aliases

8

ABL/CAN Amplification

ALK

Anaplastic Lymphoma

del(7q)

del(9p21)

Diffuse Large Cell Lymphoma

Hepatosplenic T-Cell Lymphoma

Isochromosome 7q

Large Granular Lymphocytic (LGL) Lymphoma

LGL (Large Granular Lymphocytic) Lymphoma

MLL

NHL (Non-Hodgkins Lymphoma)

Non-Hodgkins Lymphoma (NHL)

NUP214

p16

PLL (Prolymphocytic Leukemia)

Prolymphocytic Leukemia (PLL)

TCL1

Trisomy 8

Key