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Unit Code 89033:
Warfarin Sensitivity, Genotype

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Useful For

Identifying patients who may require warfarin dosing adjustments

(2,3) including:

- Patients who have previously been prescribed warfarin

  and have required multiple dosing adjustments to

  maintain the INR in the target range

- Patients with a history of thrombosis or bleeding when

  previously taking warfarin

- Patients being started on a first prescription for warfarin

Testing Algorithm

When this test is ordered, DNA extraction will always be performed

at an additional charge.

Testing Guides and Forms

• Informed Consent Form for DNA Testing 
• Multiple Drug Metabolism Genotype Tests 

Method Name

Polymerase Chain Reaction (PCR), Allele Specific Primer
Extension (ASPE)/Bead Hybridization with Fluorescence
Detection.
(PCR is utilized pursuant to a license agreement
with Roche Molecular Systems, Inc.)

Reporting Name

Warfarin Sensitivity, Genotype

Ordering Mnemonic

WARFSEN

Aliases

2C9

Coumadin Genotype

CYP2C9

Cytochrome P450 2C9 Genotyping

P450 2C9 Genotyping

Vitamin K Epoxide Reductase Subunit 1

Vitamin K Genotype (VKORC1)

VKORC1

VKORC1 and 2C9

Warfarin Genotype

Warfarin Sensitivity

Key