Unit Code 88897:
B-Cell Lymphoma, FISH, Blood or Bone Marrow
Useful For
Detecting an abnormal clone associated with the common chromosome
anomalies seen in patients with B-cell lymphoma, specifically Burkitt,
mantle cell, follicular, diffuse large B-cell, and MALT lymphoma
Individual probes can also be utilized to identify specific chromosome
anomalies in patients with B-cell lymphoma and track the response
to therapy.
Reflex Tests
| Unit Code | Reporting Name | Available Separately | Always Performed |
| 80024 | One Additional FISH Probe | No | No |
| 80025 | Two Additional FISH Probes | No | No |
| 87825 | Three Additional FISH Probes | No | No |
| 80026 | Four Additional FISH Probes | No | No |
| 87826 | Five Additional FISH Probes | No | No |
| 87827 | Six Additional FISH Probes | No | No |
| 87828 | Seven Additional FISH Probes | No | No |
| 87829 | Eight Additional FISH Probes | No | No |
| 87830 | Nine Additional FISH Probes | No | No |
| 87831 | Ten Additional FISH Probes | No | No |
| 87832 | Eleven Additional FISH Probes | No | No |
| 87833 | Twelve Additional FISH Probes | No | No |
Testing Algorithm
This test includes a mini-pathology consultation to evaluate appropriate
FISH probes and translocations to investigate. Panel includes testing
for the following anomalies via the probes listed below:
t(8;14), c-MYC/IGH
t(8q24.1;var), c-MYC
t(11;14), CCND1/IGH
t(11;18), API2/MALT1
t(14;18), IGH/MALT1
t(14;18), IGH/BCL2
t(3:var), BCL6
If the patient is being tracked for known anomalies, please indicate
which anomalies need to be investigated.
When this test is ordered, 2 FISH probes are included. If further probes
are needed, they will be added at an additional charge.
Method Name
Fluorescence In Situ Hybridization (FISH)
Reporting Name
B-Cell Lymphoma, FISH, B/BM
Ordering Mnemonic
FBLP
Aliases
3q27
API2/MALT1
BCL2/IGH
BCL6
Burkitt Lymphoma
c-MYC/IGH
CCND1/IGH
Cyclin D1
Diffuse Large Cell Lymphoma
ENMZL
FMCL
Follicular Lymphoma
IGH/MALT1
MALT Lymphoma
MALT1
Mantle Cell Lymphoma (MCL) (FISH)
Marginal Zone Lymphoma
MCL (Mantle Cell Lymphoma) FISH
t(11;14)
t(11;18)
t(14;18)
t(2;8)
t(8;14)
t(8;22)
External link
PDF document
Excel document
Word document