Test ID: FRTAL
T-Cell Acute Lymphoblastic Leukemia (T-ALL), FISH
Secondary ID 
A test code used for billing and in test definitions created prior to November 2011
NY State Approved Indicates the status of NY State approval and if the test is orderable for NY State clients.
Useful For Suggests clinical disorders or settings where the test may be helpful
Detecting a neoplastic clone associated with the common chromosome abnormalities seen in patients with T-cell acute lymphoblastic leukemia
Tracking known chromosome abnormalities and response to therapy in patients with T-cell acute lymphoblastic leukemia
Reflex Tests Lists test(s) that may or may not be performed, at an additional charge, depending on the result and interpretation of the initial test(s)
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| ADD1F | One Additional FISH Probe | No | No |
| ADD2F | Two Additional FISH Probes | No | No |
| ADD4F | Four Additional FISH Probes | No | No |
| ADD3F | Three Additional FISH Probes | No | No |
| ADD5F | Five Additional FISH Probes | No | No |
| ADD6F | Six Additional FISH Probes | No | No |
| ADD7F | Seven Additional FISH Probes | No | No |
| ADD8F | Eight Additional FISH Probes | No | No |
| ADD9F | Nine Additional FISH Probes | No | No |
| ADD10 | Ten Additional FISH Probes | No | No |
| ADD11 | Eleven Additional FISH Probes | No | No |
| ADD12 | Twelve Additional FISH Probes | No | No |
| 14FP | Fourteen Additional FISH Probes | No | No |
| 13FP | Thirteen Additional FISH Probes | No | No |
| 15FP | Fifteen Additional FISH Probes | No | No |
| 16FP | Sixteen Additional FISH Probes | No | No |
| 17FP | Seventeen Additional FISH Probes | No | No |
| 18FP | Eighteen Additional FISH Probes | No | No |
| 19FP | Nineteen Additional FISH Probes | No | No |
| 20FP | Twenty Additional FISH Probes | No | No |
| 21FP | Twenty One Additional FISH Probes | No | No |
| 22FP | Twenty Two Additional FISH Probes | No | No |
| 23FP | Twenty Three Additional FISH Probes | No | No |
| 24FP | Twenty Four Additional FISH Probes | No | No |
| 25FP | Twenty Five Additional FISH Probes | No | No |
| 26FP | Twenty Six Additional FISH Probes | No | No |
| 27FP | Twenty Seven Additional FISH Probes | No | No |
| 28FP | Twenty Eight Additional FISH Probes | No | No |
| 29FP | Twenty Nine Additional FISH Probes | No | No |
| 30FP | Thirty Additional FISH Probes | No | No |
Testing Algorithm Delineates situation(s) when tests are added to the initial order. This includes reflex and additional tests.
This panel includes analysis for the disease-associated abnormalities using the 8 probe sets listed below.
1p32, STIL/TAL1
t(5;14)(q35;q32), TLX3/BCL11B
t(7q34;var), TRB
9p-,CDKN2A/9 Cen
t(9;22)(q34;q11.2) or ABL amplification, ABL1/BCR
t(10;11)(p13;q14), MLLT10/PICALM
t(11q23;var), MLL
t(14q11.2;var), TRAD
If abnormalities are detected using either the TRAD or MLL probes, reflex testing will be performed using the following probes sets, respectively:
t(8;14)(q24.1;q11.2), MYC/TRAD
t(10;14)(q24;q11.2), TLX1/TRAD
t(11;14)(p15;q11.2), LMO1/TRAD
t(11;14)(p13;q11.2), LMO2/TRAD
t(4;11)(q21;q23), AFF1/MLL
t(6;11)(q27;q23), MLLT4/MLL
t(10;11)(p13;q23), MLLT10/MLL
t(11;19)(q23;p13.3), MLL/MLLT1
Unless specified, the 8-probe panel will be run on all specimens. If the patient has been previously identified with a specific abnormality, only those appropriate previously abnormal probe sets will be used to monitor the chromosome anomaly.
When this test is ordered, a charge for 2 FISH probes and interpretation is included. If additional probes or the entire panel are ordered, additional probe charges will be added.
Special Instructions and Forms Describes specimen collection and preparation information, test algorithms, and other information pertinent to test. Also includes pertinent information and consent forms to be used when requesting a particular test
Method Name A short description of the method used to perform the test
Fluorescence In Situ Hybridization (FISH)
Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name
Aliases Lists additional common names for a test, as an aid in searching
ABL/CAN
ABL/NUP214
ABLICAN
AF10/PICALM
CDKN2A/Cen9
Deletion 1p32
Deletion 9p
HOX11L2/BCL11B
MLL
NUP214
p16
SIL/TAL1
t(10;11)(p13;q14)
t(11q23;var)
t(14q11.2;var)
t(5;14)(q35;q32)
t(7q34;var)
t(9;22)(q34;q11.2)
T-cell receptor alpha/delta
TCRAD
TCRalpha/delta
TCRB
TCRbeta
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