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Test ID: 17PRN    
Pregnenolone and 17-Hydroxypregnenolone

Secondary ID A test code used for billing and in test definitions created prior to November 2011

88646

NY State Approved Indicates the status of NY State approval and if the test is orderable for NY State clients.

Yes

Useful For Suggests clinical disorders or settings where the test may be helpful

An ancillary test for congenital adrenal hyperplasia (CAH), particularly in situations in which a diagnosis of 21-hydroxylase and 11-hydroxylase deficiency have been ruled out.

 

Confirming a diagnosis of 3-beta-hydroxy dehydrogenase (3-beta-HSD) deficiency and 17-alpha-hydroxylase deficiency.

 

Analysis for 17-hydroxypregnenolone is also useful as part of a battery of tests to evaluate females with hirsutism or infertility. Both can result from adult-onset CAH.

Profile Information A profile is a group of laboratory tests that are ordered and performed together under a single Mayo Test ID. Profile information lists the test performed, inclusive of the test fee, when a profile is ordered and includes reporting names and individual availability.

Test IDReporting NameAvailable SeparatelyAlways Performed
PREGNPregnenolone, SYesYes
17OHP17-Hydroxypregnenolone, SYesYes

Testing Algorithm Delineates situation(s) when tests are added to the initial order. This includes reflex and additional tests.

See Steroid Pathways in Special Instructions.

Special Instructions and Forms Describes specimen collection and preparation information, test algorithms, and other information pertinent to test. Also includes pertinent information and consent forms to be used when requesting a particular test

Method Name A short description of the method used to perform the test

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name

Pregnenolone and 17-OH Pregnenolone

Aliases Lists additional common names for a test, as an aid in searching

17-Hydroxypregnenolone