Unit Code 87995:
Imatinib Mesylate Responsive Genes, Locus Anomalies, FISH
Useful For
Detecting a neoplastic clone associated with the common
chromosome anomalies seen in patients with acute leukemia
or other myeloid malignancies.
This panel is particularly useful for specimens in which standard
cytogenetic analysis is unsuccessful.
Individual probes can also be utilized to track down known
chromosome anomalies in patients with myeloid malignancies
and, therefore, assess response to therapy.
Reflex Tests
| Unit Code | Reporting Name | Available Separately | Always Performed |
| 80024 | One Additional FISH Probe | No | No |
| 80025 | Two Additional FISH Probes | No | No |
| 87825 | Three Additional FISH Probes | No | No |
| 80026 | Four Additional FISH Probes | No | No |
| 87826 | Five Additional FISH Probes | No | No |
| 87827 | Six Additional FISH Probes | No | No |
| 87828 | Seven Additional FISH Probes | No | No |
| 87829 | Eight Additional FISH Probes | No | No |
| 87830 | Nine Additional FISH Probes | No | No |
| 87831 | Ten Additional FISH Probes | No | No |
| 87832 | Eleven Additional FISH Probes | No | No |
| 87833 | Twelve Additional FISH Probes | No | No |
Testing Algorithm
Panel includes testing for the following anomalies via the probes listed:
ARG/1q25, BAP ARG
PDGFRA/4q12, BAP PDGFRA
PDGFRB/5q33, BAP PDGFRB
ABL/9q34, BAP ABL
If the patient is being tracked for known anomalies, please indicate which
anomalies need to be investigated.
When this test is ordered, 2 FISH probes are included. If further probes
are needed, they will be added at an additional charge.
Method Name
Fluorescence In Situ Hybridization (FISH)
Reporting Name
Imatinib Mesylate Resp Genes, FISH
Ordering Mnemonic
FIMRG
Aliases
1(q25)
4(q12)
5(q33)
9(q34)
ABL
ARG
PDGFRA
PDGFRB


