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Unit Code 87995:
Imatinib Mesylate Responsive Genes, Locus Anomalies, FISH

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Useful For

Detecting a neoplastic clone associated with the common

chromosome anomalies seen in patients with acute leukemia

or other myeloid malignancies.

 

This panel is particularly useful for specimens in which standard

cytogenetic analysis is unsuccessful.

 

Individual probes can also be utilized to track down known

chromosome anomalies in patients with myeloid malignancies

and, therefore, assess response to therapy.

Reflex Tests

 Unit Code  Reporting Name  Available Separately  Always Performed 
80024 One Additional FISH Probe No No
80025 Two Additional FISH Probes No No
87825 Three Additional FISH Probes No No
80026 Four Additional FISH Probes No No
87826 Five Additional FISH Probes No No
87827 Six Additional FISH Probes No No
87828 Seven Additional FISH Probes No No
87829 Eight Additional FISH Probes No No
87830 Nine Additional FISH Probes No No
87831 Ten Additional FISH Probes No No
87832 Eleven Additional FISH Probes No No
87833 Twelve Additional FISH Probes No No

Testing Algorithm

Panel includes testing for the following anomalies via the probes listed:

 

ARG/1q25, BAP ARG

PDGFRA/4q12, BAP PDGFRA

PDGFRB/5q33, BAP PDGFRB

ABL/9q34, BAP ABL

 

If the patient is being tracked for known anomalies, please indicate which

anomalies need to be investigated.

 

When this test is ordered, 2 FISH probes are included. If further probes

are needed, they will be added at an additional charge.

Method Name

Fluorescence In Situ Hybridization (FISH)

Reporting Name

Imatinib Mesylate Resp Genes, FISH

Ordering Mnemonic

FIMRG

Aliases

1(q25)

4(q12)

5(q33)

9(q34)

ABL

ARG

PDGFRA

PDGFRB


Key