Test ID: CVID
Common Variable Immunodeficiency Confirmation Flow Panel
Secondary ID 
A test code used for billing and in test definitions created prior to November 2011
87993
NY State Approved Indicates the status of NY State approval and if the test is orderable for NY State clients.
Yes
Useful For Suggests clinical disorders or settings where the test may be helpful
Screening for common variable immunodeficiency (CVID)
Identifying defects in TACI and BAFF-R in patients presenting with clinical symptoms and other laboratory features consistent with CVID
Evaluating B cell immune competence by assessing expression of BAFF-R and TACI proteins
Useful for assessing BAFF-R and TACI protein expression and frequency of B cells bearing these receptors. TNFRSF13C (BAFF-R) and TNFRSF13B (TACI) gene mutations have been described in a small subset of patients with humoral immunodeficiencies classified as CVID. The majority of TNFRSF13B mutations preserve TACI protein expression and require genetic testing to identify pathogenic or potentially pathogenic mutations/variants.
Method Name A short description of the method used to perform the test
Fluorescent Flow Cytometry
Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name
CVID Confirmation Flow Panel
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