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Unit Code 87980:
BRAF Mutation Analysis (V600E), Tumor

Useful For Suggests clinical disorders or settings where the test may be helpful

As an adjunct to #17073 "Hereditary Nonpolyposis Colorectal Cancer

(HNPCC) Screen," when tumor demonstrates MSI-H and loss of MLH1

protein expression, to help distinguish a somatic versus germline event

prior to performing expensive germline testing

 

As an adjunct to negative MLH1 germline testing in cases where

clinical suspicion is high and when tumor from the same patient

demonstrates MSI-H and loss of MLH1 protein expression

 

Note: Mayo's preferred screening test (#87931 "MLH1

Hypermethylationand BRAF Mutation Analyses") includes both MLH1

promoter hypermethylation and BRAF V600E testing.

Special Instructions and Forms Describes specimen collection and preparation information, test algorithms, and other information pertinent to test. Also includes pertinent information and consent forms to be used when requesting a particular test

Method Name A short description of the method used to perform the test

Polymerase Chain Reaction (PCR) Analysis
(PCR is utilized pursuant to a license agreement with Roche
Molecular Systems, Inc.)

Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name

BRAF Mutation Analysis(V600E),Tumor

Ordering Mnemonic An alternate Mayo code (to the Unit Code) for a test

BRAF

Aliases Lists additional common names for a test, as an aid in searching

Soft-BRAF

V600E