Unit Code 87980:
BRAF Mutation Analysis (V600E), Tumor
Useful For 
Suggests clinical disorders or settings where the test may be helpful
As an adjunct to #17073 "Hereditary Nonpolyposis Colorectal Cancer
(HNPCC) Screen," when tumor demonstrates MSI-H and loss of MLH1
protein expression, to help distinguish a somatic versus germline event
prior to performing expensive germline testing
As an adjunct to negative MLH1 germline testing in cases where
clinical suspicion is high and when tumor from the same patient
demonstrates MSI-H and loss of MLH1 protein expression
Note: Mayo's preferred screening test (#87931 "MLH1
Hypermethylationand BRAF Mutation Analyses") includes both MLH1
promoter hypermethylation and BRAF V600E testing.
Special Instructions and Forms Describes specimen collection and preparation information, test algorithms, and other information pertinent to test. Also includes pertinent information and consent forms to be used when requesting a particular test
| • | Molecular Genetics - Inherited Cancer Syndromes Patient Information Sheet |
| • | Informed Consent for DNA Testing |
| • | Hereditary Nonpolyposis Colorectal Cancer Testing Algorithm |
Method Name A short description of the method used to perform the test
Polymerase Chain Reaction (PCR) Analysis
(PCR is utilized pursuant to a license agreement with Roche
Molecular Systems, Inc.)
Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name
BRAF Mutation Analysis(V600E),Tumor
Ordering Mnemonic An alternate Mayo code (to the Unit Code) for a test
BRAF
Aliases Lists additional common names for a test, as an aid in searching
Soft-BRAF
V600E
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