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Unit Code 87894:
Acute Myeloid Leukemia (AML), FISH

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Useful For

Detecting a neoplastic clone associated with the common chromosome

anomalies seen in patients with AML or other myeloid malignancies

 

Evaluating specimens in which standard cytogenetic analysis is

unsuccessful

 

Identifying known chromosome anomalies in patients with myeloid

malignancies and tracking response to therapy

Reflex Tests

 Unit Code  Reporting Name  Available Separately  Always Performed 
87831 Ten Additional FISH Probes No No
87832 Eleven Additional FISH Probes No No
87833 Twelve Additional FISH Probes No No
80024 One Additional FISH Probe No No
80025 Two Additional FISH Probes No No
87825 Three Additional FISH Probes No No
80026 Four Additional FISH Probes No No
87826 Five Additional FISH Probes No No
87827 Six Additional FISH Probes No No
87828 Seven Additional FISH Probes No No
87829 Eight Additional FISH Probes No No
87830 Nine Additional FISH Probes No No

Testing Algorithm

Please indicate subtype as well as which anomalies need to be

investigated from the following profile:

 

t(8:21), [M2], ETO/AML1

t(15:17), [M3], PML/RARA

t(11q23:var), [M0-M7], MLL

inv(16), [M4, Eos], MYH11/CBFb

8, [M0-M7], Cen8/c-MYC

t(6;9), [M2, M4], DEK/CAN

inv(3),  [M1, 2,4,6,7] RPN/EVI1

 

If the patient is being treated for known anomalies, please indicate

which anomalies need to be investigated.

 

When this test is ordered, 2 FISH probes are included. If further probes

are needed, they will be added at an additional charge.

Special Instructions and Forms

• Cytogenetics Hematologic FISH Panel Patient Information Sheet 

Method Name

Fluorescence In Situ Hybridization (FISH)

Reporting Name

AML, FISH

Ordering Mnemonic

FAML

Aliases

11q23

Acute Myeloid Leukemia (AML)

Acute Promyelocytic Leukemia (APL)

AF9/MLL

AML-M2

AML-M3

AML-M4

AML-M4eo

AML-M5

APL (Acute Promyelocytic Leukemia)

DEK/CAN

ETO/AML1

FISH (Fluorescence In Situ Hybridization)

Inv(16)

Inv(3)

inversion 16

inversion 3

MLL

MYH11/CBFb

NUP214

PML/RARA

t(15;17)

t(16;16)

t(3;3)

t(6;9)

t(8;21)

t(9;11)

Key