|Values are valid only on day of printing.|
Preferred test for detection of metachromatic leukodystrophy
Preferred test to rule out metachromatic leukodystrophy. Not reliable in identifying carriers due to analytical variation and unusual genetic variants.
Metachromatic leukodystrophy (MLD) presents with progressive neurologic changes and leukodystrophy with variable age of onset
Arylsulfatase A enzyme levels are decreased in individuals with MLD, and excessive amounts of sulfatides are present in urine
Decreased arylsulfatase A enzyme levels can be seen in unaffected individuals who have a pseudodeficiency of arylsulfatase A
Colorimetric Enzyme Assay