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Test Catalog

Test ID: PPFE    
Protoporphyrins, Fractionation, Whole Blood

NY State Approved Indicates the status of NY State approval and if the test is orderable for NY State clients.


Useful For Suggests clinical disorders or settings where the test may be helpful

Establishing a biochemical diagnosis of erythropoietic protoporphyria


Differential diagnosis of chronic intoxication from exposure to a variety of causes including heavy metals and chemicals


Differential diagnosis in some cases of iron-deficiency anemia

Genetics Test Information Provides information that may help with selection of the correct test or proper submission of the test request

Includes separate quantitation of zinc protoporphyrin and free protoporphyrin. Abstinence from alcohol is essential for at least 24 hours as alcohol suppresses enzyme activity, potentially leading to falsely increased results.

Testing Algorithm Delineates situation(s) when tests are added to the initial order. This includes reflex and additional tests.

The following algorithms are available in Special Instructions: 

-Porphyria (Acute) Testing Algorithm

-Porphyria (Cutaneous) Testing Algorithm

Special Instructions and Forms Describes specimen collection and preparation information, test algorithms, and other information pertinent to test. Also includes pertinent information and consent forms to be used when requesting a particular test

Method Name A short description of the method used to perform the test

High-Performance Liquid Chromatography (HPLC) with Fluorescence Detection
Includes separate quantitation of zinc protoporphyrins and free protoporphyrins.

Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name

Protoporphyrins, Fractionation, WB

Aliases Lists additional common names for a test, as an aid in searching

EPP (Erythropoietic Protoporphyria)
Erythropoietic Protoporphyria
Free Protoporphyrin
Zinc Protoporphyrin