Test ID: PPFE
Protoporphyrins, Fractionation, Whole Blood
Secondary ID 
A test code used for billing and in test definitions created prior to November 2011
Useful For Suggests clinical disorders or settings where the test may be helpful
Establishing a biochemical diagnosis of erythropoietic protoporphyria.
Differential diagnosis of chronic intoxication from exposure to a variety of causes including heavy metals and chemicals.
Differential diagnosis in some cases of iron-deficiency anemia.
There are 2 test options: whole blood (PPFE/8739 Protoporphyrins, Fractionation, Whole Blood) and washed RBCs (PPFWE/31891 Protoporphyrins, Fractionation, Washed Erythrocytes). The whole blood option is easiest for clients but requires that the specimen arrive at Mayo Medical Laboratories within 72 hours of draw. When this cannot be ensured, washed RBCs should be submitted.
Genetics Test Information Provides information that may help with selection of the correct test or proper submission of the test request
Includes separate quantitation of zinc protoporphyrin and free protoporphyrin. Abstinence from alcohol is essential for at least 24 hours as alcohol suppresses enzyme activity, potentially leading to falsely increased results.
Testing Algorithm Delineates situation(s) when tests are added to the initial order. This includes reflex and additional tests.
The following algorithms are available in Special Instructions:
-Porphyria (Acute) Testing Algorithm
-Porphyria (Cutaneous) Testing Algorithm
Special Instructions and Forms Describes specimen collection and preparation information, test algorithms, and other information pertinent to test. Also includes pertinent information and consent forms to be used when requesting a particular test
Method Name A short description of the method used to perform the test
High-Performance Liquid Chromatography (HPLC) with Fluorescence Detection
Includes separate quantitation of zinc protoporphyrins and free protoporphyrins.
Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name
Aliases Lists additional common names for a test, as an aid in searching
Erythropoietic Protoporphyria
Free Protoporphyrin
Zinc Protoporphyrin
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