|Values are valid only on day of printing.|
Diagnosing viral infections
All routine viral cultures are inoculated into cell culture tubes for viral detection. The most common specimens received for routine testing include body fluid, ocular, rectal, spinal fluid, and stool. A rapid (16-hour incubation) shell vial cell culture assay will be inoculated when specimens are designated for herpes simplex virus (HSV) or cytomegalovirus (CMV) detection or as appropriate for source indicated.
Blood, lymph node tissue, and bone marrow/bone tissue specimens are not productive and frequently toxic in culture. Most molecular methods are appropriate for these specimen types (exception is bone tissue). See individual real-time PCR assay test descriptions.
Genital, synovial fluid, wound swab or tissue (includes pus, drainage, or abscess fluid) specimens are not acceptable for viral culture.
Oral specimens submitted for culture should be ordered as VRESP / Viral Culture, Respiratory.
Dermal specimens are only acceptable for enterovirus culture:
-For dermal specimens for hand-foot-and-mouth disease or enterovirus, clearly indicate "enterovirus" on request.
Urine specimens are only acceptable for mumps culture. For urine specimens, clearly indicate "mumps" on request.
For requests to rule-out HSV infection in neonates (<1 month) on dermal specimens, order VHSV / Herpes Simplex Virus (HSV), Culture From Neonates.
Do not submit specimens for viral culture testing if there is a suspicion of Ebola virus or any viral hemorrhagic fever, avian influenza, severe acute respiratory syndrome (SARS), Middle Eastern Respiratory Syndrome Coronovirus (MERS-CoV), or other high-risk infectious agents. Contact your state health department for more information and testing options.
For requests for CMV on bone marrow or urine specimen, see:
-LCMV / Cytomegalovirus (CMV), Molecular Detection, PCR
For requests for HSV/varicella-zoster virus on genital or dermal specimen, see:
-LHSV / Herpes Simplex Virus (HSV), Molecular Detection, PCR
-LVZV / Varicella-Zoster Virus, Molecular Detection, PCR
-LHSVZ / Herpes Simplex Virus (HSV) and Varicella-Zoster Virus (VZV), Molecular Detection, PCR
Shell Vial Assay for Herpes Simplex Virus or Cytomegalovirus