HYOX - Overview: Hyperoxaluria Panel, Urine

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Test ID: HYOX    
Hyperoxaluria Panel, Urine

Useful For Suggests clinical disorders or settings where the test may be helpful

Distinguishing between primary and secondary hyperoxaluria

 

Distinguishing between primary hyperoxaluria types 1, 2, and 3

Genetics Test Information Provides information that may help with selection of the correct test or proper submission of the test request

Distinguishing among primary hyperoxaluria types 1, 2, and 3, and secondary hyperoxaluria.

Highlights

Primary hyperoxalurias (PH), classified into types 1, 2, and 3, are genetic disorders of oxalate metabolism characterized by increased urinary excretion of oxalic acid and kidney stone formation.

 

Secondary hyperoxaluria is an acquired condition resulting from either increased intake of dietary oxalate or altered intestinal oxalate absorption.

 

A diagnostic workup in an individual with hyperoxaluria demonstrates increased concentration of oxalate in urinary metabolite screening. If glycolate, glycerate, or 4-hydroxy-2-oxoglutarate is present, a primary hyperoxaluria is indicated.

 

Each type is distinguished from the others based on the urine profile.

 

Ascorbic acid will falsely elevate oxalic acid results.

Testing Algorithm Delineates situation(s) when tests are added to the initial order. This includes reflex and additional tests.

See Hyperoxaluria Diagnostic Algorithm in Special Instructions.

Special Instructions and Forms Describes specimen collection and preparation information, test algorithms, and other information pertinent to test. Also includes pertinent information and consent forms to be used when requesting a particular test

Method Name A short description of the method used to perform the test

Gas Chromatography-Mass Spectrometry (GC-MS)

NY State Approved Indicates the status of NY State approval and if the test is orderable for NY State clients.

Conditional

Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name

Hyperoxaluria Panel, U

Aliases Lists additional common names for a test, as an aid in searching

Glycerate
Glycolate
Oxalate
PH1 (Primary Hyperoxaluria Type 1)
PH2 (Primary Hyperoxaluria Type 2)
Primary Hyperoxaluria Type 1 (PH1)
Primary Hyperoxaluria Type 2 (PH2)
4-hydroxy-2-oxoglutarate
HOG
HOGA1
PH3 (Primary Hyperoxaluria Type 3)
Primary Hyperoxaluria Type 3 (PH3)

Key