Test ID: TACIF
Transmembrane Activator and CAML Interactor (TACI) Gene, Full Gene Analysis
Secondary ID 
A test code used for billing and in test definitions created prior to November 2011
Useful For Suggests clinical disorders or settings where the test may be helpful
Evaluating individuals with:
-Common variable immunodeficiency (CVID)
-Clinically symptomatic selective IgA deficiency
-Lymphoproliferative disease associated with CVID
-Autoimmune phenotypes with CVID
These clinical features may be consistent with possible TACI mutations, and the genotyping test is especially useful as a follow-up test when flow cytometry is uninformative.
Identification of specific TACI mutations in individuals with abnormal TACI flow cytometry results (from IABCS/88800 B-Cell Phenotyping Profile for Immunodeficiency and Immune Competence Assessment, Blood).
Profile Information A profile is a group of laboratory tests that are ordered and performed together under a single Mayo Test ID. Profile information lists the test performed, inclusive of the test fee, when a profile is ordered and includes reporting names and individual availability.
| Test ID | Secondary ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|---|
| TACIS | 28582 | TACI, Full Gene Sequence | No | Yes |
| TACI | 89202 | TACI Gene Sequencing | No | Yes |
Additional Tests Lists test(s) that are always performed, at an additional charge, with the initial test(s)
| Test ID | Test Number | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|---|
| NPLXT | 81769 | Rapid DNA Extraction | No | Yes |
Testing Algorithm Delineates situation(s) when tests are added to the initial order. This includes reflex and additional tests.
When this test is ordered, a DNA extraction will always be performed at an additional charge.
Special Instructions and Forms Describes specimen collection and preparation information, test algorithms, and other information pertinent to test. Also includes pertinent information and consent forms to be used when requesting a particular test
Method Name A short description of the method used to perform the test
Polymerase Chain Reaction (PCR) Followed by DNA Sequence Analysis
(PCR is utilized pursuant to a license agreement with Roche Molecular Systems, Inc.)
Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name
Aliases Lists additional common names for a test, as an aid in searching
APRIL receptor
Autoimmune cytopenias
B-cells
BAFF receptor
Common variable immunodeficiency
CVID
Hypogammaglobulinemia
IgA deficiency
Isotype class switching
Malignancy in CVID
sIgAD
T-cell-independent antibody response
TACI
TNFRSF13B
Transmembrane Activator and CAML interactor
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