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Unit Code 83949:
UDP-Glycuronosyl Transferase 1A1 TA Repeat Genotype, UGT1A1

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Useful For

Identifying individuals who are at increased risk of adverse

drug reactions with irinotecan and who should be considered

for decreased dosing of the drug  

 

Confirmation of a diagnosis of Gilbert syndrome

Testing Algorithm

When this test is ordered, DNA extraction will always be performed

at an additional charge. However, for multiple drug metabolism

genotype test orders, only a single specimen is needed; and the

DNA extraction will only be charged once.

Special Instructions and Forms

• Informed Consent Form for DNA Testing 
• Multiple Drug Metabolism Genotype Tests 

Method Name

Polymerase Chain Reaction (PCR)
(PCR is utilized pursuant to a license agreement
with Roche Molecular Systems, Inc.)

Reporting Name

UGT1A1 TA Repeat Genotype

Ordering Mnemonic

U1A1

Aliases

GNT1

Irinotecan glucuronidation

Irinotecan metabolism

Phenol/Bilirubin UDP-Glucuronosyltransferase

UDP-Glycosyltransferase 1

UGT1A1

Uracil Glucuronyl transferase

Uridine Diphosphate Glycosyltransferase 1

Key