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Unit Code 83631:
Connective Tissue Diseases Cascade, Serum

Useful For Suggests clinical disorders or settings where the test may be helpful

This test is designed to evaluate patients with signs and symptoms

compatible with connective tissue diseases. The testing algorithm is

useful in the initial evaluation of patients and performs best in clinical

situations in which the prevalence of disease is low.(2)

Profile Information A profile is a group of laboratory tests that are ordered and performed together under a single Unit Code. Profile information lists tests performed, inclusive of the test fee, when a profile is ordered and includes reporting names and individual availability.

 Unit Code  Reporting Name  Available Separately  Always Performed 
 9026   Antinuclear Ab, S Yes Yes
 84182   Cyclic Citrullinated Peptide Ab, S Yes Yes

Reflex Tests Lists test(s) that may or may not be performed, at an additional charge, depending on the result and interpretation of the initial test(s)

 Unit Code  Reporting Name  Available Separately  Always Performed 
8178 DNA Double-Stranded Ab, IgG, S Yes No
89035 Ab to Extractable Nuclear Ag Eval, S Yes No
87837 Ribosome P Ab, IgG, S Yes No
9278 Centromere Ab, IgG, S Yes No
7586 ANA2 Cascade No No

Testing Algorithm Delineates situation(s) when tests are added to the initial order. This includes reflex and additional tests.

If antinuclear antibodies are > or =3.0 U, then antibodies to

double-stranded DNA (ds-DNA), extractable nuclear antigen

evaluation, ribosome P, and centromere are performed at an

additional charge.

Special Instructions and Forms Describes specimen collection and preparation information, test algorithms, and other information pertinent to test. Also includes pertinent information and consent forms to be used when requesting a particular test

• Connective Tissue Diseases Cascade Test-Ordering Algorithm 

Method Name A short description of the method used to perform the test

84182: Enzyme Immunoassay (EIA)

9026: Enzyme-Linked Immunosorbent Assay (ELISA)

8178, 89035, 87837, 9278: Multiplex Flow Immunoassay

General Information:

See "Connective Tissue Diseases Cascade Test-Ordering Algorithm"

in Special Instructions.

Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name

Connective Tissue Diseases Cascade

Ordering Mnemonic An alternate Mayo code (to the Unit Code) for a test

CTDC

Aliases Lists additional common names for a test, as an aid in searching

Ab to Extractable Nuclear Ag

ANA (Antinuclear Antibodies)

ANA Reflex Testing

ANA Test algorithm

Anti-CCP (Cyclic Citrullinated Peptide)

Anti-Citrullinated Antibody

Anti-Cyclic Citrullinated Peptide (CCP)

Anti-DNA

Anti-ds (Anti-Double-Stranded) DNA

Anti-ENA (Antibodies to Extractable Nuclear Antigens)

Anti-La

Anti-Ribonuclear Protein

Anti-Ribosome P Antibodies

Anti-RNP (Anti-Ribonucleoprotein)

Anti-Ro

Anti-Sjogren's Syndrome

Anti-Sm (Smith)

Anti-Smith (Sm) Antigen

Anti-SSA (Anti-Sjogren's Syndrome A)

Anti-SSB (Anti-Sjogren's Syndrome B)

Anti-U(1)RNP (Anti-Ribonucleoprotein)

Antibodies to Extractable Nuclear Antigens

Antibody to Native DNA (n-DNA)

Antinuclear Ab

Antinuclear Antibodies (ANA)

Autoantibodies to Jo 1 Antigen

Autoantibodies to Jo1

Autoantibodies to Scl 70

Autoantibodies to Scl 70 Antigen

Autoantibodies to Sm (Smith)

Autoantibodies to SSA (Ro)

Autoantibodies to SSB (La)

Autoantibodies to U(1)RNP

Cascade

CCP (Cyclic Citrullinated Peptide)

Centromere Antibodies, IgG

Citrullinated Antibody

Connective Tissue

Connective Tissue Disease algorithm

Connective Tissue Disease panel

Cyclic Citrullinated Peptide Antibodies

DNA Double-Stranded (ds-DNA) Antibody

DNA Topoisomerase 1 Antibodies

DNA, Anti

ENA (Extractable Nuclear Antigens), Anti

Extractable Nuclear Antigens, Anti

Histidyl-tRNA Synthetase Antibodies

Jo 1 Antibodies

La (Anti-SSB)

LE (Lupus Erythematosus)

Lupus

Lupus algorithm

Lupus Cascade

Lupus Erythematosus (LE)

Lupus Profile

Polymyositis Antibodies

Ribonucleoprotein (RNP) Autoantibodies

RNA (Ribonucleoprotein) Autoantibodies)

Ro (Anti-SSA)

Scl 70 Antibodies

Scleroderma Antibodies

Sjogren's Syndrome

SLE (Systemic Lupus Erythematosus)

Sm (Anti-Sm) Smith

Smith Antigen, Anti

SmRNP Autoantibodies

Soft-CTDC

SSA (Anti-SSA)

SSB (Anti-SSB)

Systemic Lupus Erythematosus (SLE)

Tissue, Connective

Topoisomerase 1 Antibodies

U(1)RNP (Ribonucleoprotein) Autoantibodies