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Unit Code 83371:
Myasthenia Gravis (MG) Evaluation, Pediatric

Useful For Suggests clinical disorders or settings where the test may be helpful

Recommended for initial investigation of patients presenting

at less than age 20 with a defect of neuromuscular transmission

 

Confirming that a recently acquired neurological disorder has

an autoimmune basis

 

Distinguishing acquired MG from congenital myasthenic

syndromes (persistently seronegative)

 

Providing a quantitative baseline for future comparisons

in monitoring clinical course and response to immunomodulatory

treatment

 

Note:  Single antibody tests may be requested in follow-up of

              patients with positive results documented in this laboratory.

Profile Information A profile is a group of laboratory tests that are ordered and performed together under a single Unit Code. Profile information lists tests performed, inclusive of the test fee, when a profile is ordered and includes reporting names and individual availability.

 Unit Code  Reporting Name  Available Separately  Always Performed 
 8338   ACh Receptor (Muscle) Binding Ab Yes Yes
 83378   ACh Receptor (Muscle) Modulating Ab No Yes

Special Instructions and Forms Describes specimen collection and preparation information, test algorithms, and other information pertinent to test. Also includes pertinent information and consent forms to be used when requesting a particular test

• Myasthenia Gravis: Pediatric Diagnostic Algorithm 

Method Name A short description of the method used to perform the test

Radioimmunoassay (RIA)

General Information:

Recommended for initial investigation of patients presenting

at less than age 20 with a defect of neuromuscular transmission.

Seropositivity distinguishes congenital (i.e., genetic) MG from

acquired MG. Seronegativity does not exclude the diagnosis

of autoimmune MG. A minority of patients lacking detectable

AChR antibodies have the recently discovered muscle-specific

receptor tyrosine kinase antibodies.

See "Myasthenia Gravis: Pediatric Diagnostic Algorithm" in

Special Instructions.

Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name

MG Eval, Pediatric

Ordering Mnemonic An alternate Mayo code (to the Unit Code) for a test

MGEP

Aliases Lists additional common names for a test, as an aid in searching

Acetylcholine Receptor (Muscle AChR) Antibodies

AChR (Acetylcholine Receptor)

Muscle End-Plate Antibodies

Myasthenia Gravis Antibodies

Myoid Antibody

Soft-MGEP