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Test ID: 83343    
ThinPrep Diagnostic with Human Papillomavirus (HPV) Reflex

Useful For Suggests clinical disorders or settings where the test may be helpful

Management and triage of patient's, age 21 or greater, with abnormal Pap results


Human papillomavirus (HPV) testing detection of high-risk genotypes associated with the development of cervical cancer


Results can be used as an aid in triaging women with abnormal Pap smear results


Individual genotyping of HPV-16 or HPV-18, if present


Results of HPV-16 and HPV-18 genotyping can be used as an aid in triaging women with positive high risk HPV (HR-HPV) but negative Pap smear results.

Reflex Tests Lists test(s) that may or may not be performed, at an additional charge, depending on the result and interpretation of the initial test(s)

Test IDReporting NameAvailable SeparatelyAlways Performed
88141Phys Interp of Diag PAPNoNo
70099High Risk HPV with GenotypingYes, (order #62598 HPV)No

Testing Algorithm Delineates situation(s) when tests are added to the initial order. This includes reflex and additional tests.

When this test is ordered, a ThinPrep Pap diagnostic test will be performed. If the results include the criteria below, a high-risk HPV test will be performed:

-Atypical cells of undetermined significance (ASCUS), and the patient is > or =21 years old

-Atypical squamous cells, cannot exclude high-grade squamous intraepithelial lesion (ASC-H) and the patient is > or =21 years old

-Low-grade squamous intraepithelial lesion (LSIL), and the patient is > or =50 years old

-Inadequate endocervical/transformation zone component, negative for intraepithelial lesion or malignancy, and the patient is > or =30 years old


If ThinPrep Pap results are abnormal, a pathologist will review the case at an additional charge.

Special Instructions and Forms Describes specimen collection and preparation information, test algorithms, and other information pertinent to test. Also includes pertinent information and consent forms to be used when requesting a particular test

Method Name A short description of the method used to perform the test

ThinPrep Pap Cytology Screening by Light Microscopy with HPV High-Risk DNA Detection with Genotyping by Real-Time Polymerase Chain Reaction

(PCR is utilized pursuant to a license agreement with Roche Molecular Systems, Inc.)

NY State Approved Indicates the status of NY State approval and if the test is orderable for NY State clients.


Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name

ThinPrep Diagnostic with HPV Reflex

Aliases Lists additional common names for a test, as an aid in searching