Test ID: FCLL
Chronic Lymphocytic Leukemia (CLL), FISH
Secondary ID 
A test code used for billing and in test definitions created prior to November 2011
NY State Approved Indicates the status of NY State approval and if the test is orderable for NY State clients.
Useful For Suggests clinical disorders or settings where the test may be helpful
Detecting clones with abnormalities of chromosomes 6, 11, 12, 13, 14, 17, 18, or 19 in patients with B-cell chronic lymphocytic leukemia (B-CLL)
Quantifying disease before and after therapy in patients with B-CLL
Distinguishing patients with 11;14 translocations who have leukemic phase of mantle cell lymphoma from patients who have B-CLL
Detecting patients with atypical B-CLL or other forms of lymphoma associated with 14;18 or 14;19 translocations
Reflex Tests Lists test(s) that may or may not be performed, at an additional charge, depending on the result and interpretation of the initial test(s)
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| ADD1F | One Additional FISH Probe | No | No |
| ADD2F | Two Additional FISH Probes | No | No |
| ADD4F | Four Additional FISH Probes | No | No |
| ADD3F | Three Additional FISH Probes | No | No |
| ADD5F | Five Additional FISH Probes | No | No |
| ADD6F | Six Additional FISH Probes | No | No |
| ADD7F | Seven Additional FISH Probes | No | No |
| ADD8F | Eight Additional FISH Probes | No | No |
| ADD9F | Nine Additional FISH Probes | No | No |
| ADD10 | Ten Additional FISH Probes | No | No |
| ADD11 | Eleven Additional FISH Probes | No | No |
| ADD12 | Twelve Additional FISH Probes | No | No |
| 14FP | Fourteen Additional FISH Probes | No | No |
| 13FP | Thirteen Additional FISH Probes | No | No |
| 15FP | Fifteen Additional FISH Probes | No | No |
| 16FP | Sixteen Additional FISH Probes | No | No |
| 17FP | Seventeen Additional FISH Probes | No | No |
| 18FP | Eighteen Additional FISH Probes | No | No |
| 19FP | Nineteen Additional FISH Probes | No | No |
| 20FP | Twenty Additional FISH Probes | No | No |
| 21FP | Twenty One Additional FISH Probes | No | No |
| 22FP | Twenty Two Additional FISH Probes | No | No |
| 23FP | Twenty Three Additional FISH Probes | No | No |
| 24FP | Twenty Four Additional FISH Probes | No | No |
| 25FP | Twenty Five Additional FISH Probes | No | No |
| 26FP | Twenty Six Additional FISH Probes | No | No |
| 27FP | Twenty Seven Additional FISH Probes | No | No |
| 28FP | Twenty Eight Additional FISH Probes | No | No |
| 29FP | Twenty Nine Additional FISH Probes | No | No |
| 30FP | Thirty Additional FISH Probes | No | No |
Testing Algorithm Delineates situation(s) when tests are added to the initial order. This includes reflex and additional tests.
FISH testing is recommended in place of chromosome analysis for this disorder. This panel includes testing for the following anomalies via the probes listed:
6q-, MYB/Cen6
11q-, ATM/Cen11
+12, D12Z3/MDM2
13q-, D13S319/LAMP1
17p-, TP53/Cen17
t(11;14), CCND1/IGH
Reflex for IGH anomaly:
t(14;18), IGH/BCL2
t(14;18), IGH/BCL3
If the patient is being tracked for known anomalies, indicate which anomalies need to be investigated.
When this test is ordered, 12 FISH probes are included. If further probes beyond the initial 12 are needed, they will be added at an additional charge.
Special Instructions and Forms Describes specimen collection and preparation information, test algorithms, and other information pertinent to test. Also includes pertinent information and consent forms to be used when requesting a particular test
Method Name A short description of the method used to perform the test
Fluorescence In Situ Hybridization (FISH)
Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name
Aliases Lists additional common names for a test, as an aid in searching
ATM
c-MYB
CCND1-XT
Chromosome Analysis by FISH Panel for Chronic Lymphocytic
Chronic Lymphocytic Leukemia (CLL)
CLL (Chronic Lymphocytic Leukemia)
Deletion 11q
Deletion 13q
Deletion 17p
Deletion 6p
FISH for Chronic Lymphocytic Leukemia
FISH for CLL (Chronic Lymphocytic Leukemia)
IGH
LAMP1
Leukemia CLL (Chronic Lymphocytic Leukemia)
p53
t(11:14)
MYB
TP53
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