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Test ID: FCLL    
Chronic Lymphocytic Leukemia (CLL), FISH

Secondary ID A test code used for billing and in test definitions created prior to November 2011

83089

NY State Approved Indicates the status of NY State approval and if the test is orderable for NY State clients.

Yes

Useful For Suggests clinical disorders or settings where the test may be helpful

Detecting a neoplastic clone associated with the common chromosome abnormalities seen in patients with chronic lymphocytic leukemia (CLL)

 

Identifying and tracking known chromosome abnormalities in patients with CLL and tracking response to therapy

 

Distinguishing patients with 11;14 translocations who have leukemic phase of mantle cell lymphoma from patients who have CLL 

 

Detecting patients with atypical CLL or other forms of lymphoma associated with translocations between IGH and BCL2, BCL3, MYC, or other partner genes

Reflex Tests Lists test(s) that may or may not be performed, at an additional charge, depending on the result and interpretation of the initial test(s)

Test IDReporting NameAvailable SeparatelyAlways Performed
ADD1FOne Additional FISH ProbeNoNo
ADD2FTwo Additional FISH ProbesNoNo
ADD4FFour Additional FISH ProbesNoNo
ADD3FThree Additional FISH ProbesNoNo
ADD5FFive Additional FISH ProbesNoNo
ADD6FSix Additional FISH ProbesNoNo
ADD7FSeven Additional FISH ProbesNoNo
ADD8FEight Additional FISH ProbesNoNo
ADD9FNine Additional FISH ProbesNoNo
ADD10Ten Additional FISH ProbesNoNo
ADD11Eleven Additional FISH ProbesNoNo
ADD12Twelve Additional FISH ProbesNoNo
14FPFourteen Additional FISH ProbesNoNo
13FPThirteen Additional FISH ProbesNoNo
15FPFifteen Additional FISH ProbesNoNo
16FPSixteen Additional FISH ProbesNoNo
17FPSeventeen Additional FISH ProbesNoNo
18FPEighteen Additional FISH ProbesNoNo
19FPNineteen Additional FISH ProbesNoNo
20FPTwenty Additional FISH ProbesNoNo
21FPTwenty One Additional FISH ProbesNoNo
22FPTwenty Two Additional FISH ProbesNoNo
23FPTwenty Three Additional FISH ProbesNoNo
24FPTwenty Four Additional FISH ProbesNoNo
25FPTwenty Five Additional FISH ProbesNoNo
26FPTwenty Six Additional FISH ProbesNoNo
27FPTwenty Seven Additional FISH ProbesNoNo
28FPTwenty Eight Additional FISH ProbesNoNo
29FPTwenty Nine Additional FISH ProbesNoNo
30FPThirty Additional FISH ProbesNoNo

Testing Algorithm Delineates situation(s) when tests are added to the initial order. This includes reflex and additional tests.

When this test is ordered, a charge for 2 FISH probes and interpretation is included. If additional probes or the entire panel are ordered, additional probe charges will be added.

 

Please indicate if the entire panel is to be performed. The entire panel is suggested for newly diagnosed patients. If the patient is being tracked for known anomalies or disease progression, indicate which probe sets need to be investigated.

6q-, Cen6/MYB

11q-, Cen11/ATM

+12, Cen12/MDM2

13q-, D13S319/LAMP1

17p-, TP53/Cen17

t(11;14), CCND1/IGH

 

When an IGH rearrangement is identified, reflex testing is performed to identify the translocation partner. Probes include identification of t(14;18)(q32;q21) IGH/BCL2 and t(14;19)(q32;q13) IGH/BCL3.

Special Instructions and Forms Describes specimen collection and preparation information, test algorithms, and other information pertinent to test. Also includes pertinent information and consent forms to be used when requesting a particular test

Method Name A short description of the method used to perform the test

Fluorescence In Situ Hybridization (FISH)

Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name

CLL, FISH

Aliases Lists additional common names for a test, as an aid in searching

+12
ATM
Deletion 11q
Deletion 13q
Deletion 17p
Deletion 6p
IGH
LAMP1
p53
t(11:14)
TP53
CCND1
MYB