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Test ID: FCLL
Chronic Lymphocytic Leukemia (CLL), FISH

Secondary ID A test code used for billing and in test definitions created prior to November 2011

83089

Useful For Suggests clinical disorders or settings where the test may be helpful

Detecting clones with abnormalities of chromosomes 6, 11, 12, 13, 14, 17, 18, or 19 in patients with B-cell chronic lymphocytic leukemia (B-CLL)

 

Quantifying disease before and after therapy in patients with B-CLL

 

Distinguishing patients with 11;14 translocations who have leukemic phase of mantle cell lymphoma from patients who have B-CLL

 

Detecting patients with atypical B-CLL or other forms of lymphoma associated with 14;18 or 14;19 translocations

Reflex Tests Lists test(s) that may or may not be performed, at an additional charge, depending on the result and interpretation of the initial test(s)

Test IDSecondary IDReporting NameAvailable SeparatelyAlways Performed
ADD1F80024One Additional FISH ProbeNoNo
ADD2F80025Two Additional FISH ProbesNoNo
ADD4F80026Four Additional FISH ProbesNoNo
ADD3F87825Three Additional FISH ProbesNoNo
ADD5F87826Five Additional FISH ProbesNoNo
ADD6F87827Six Additional FISH ProbesNoNo
ADD7F87828Seven Additional FISH ProbesNoNo
ADD8F87829Eight Additional FISH ProbesNoNo
ADD9F87830Nine Additional FISH ProbesNoNo
ADD1087831Ten Additional FISH ProbesNoNo
ADD1187832Eleven Additional FISH ProbesNoNo
ADD1287833Twelve Additional FISH ProbesNoNo
14FP89714Fourteen Additional FISH ProbesNoNo
13FP89741Thirteen Additional FISH ProbesNoNo
15FP89715Fifteen Additional FISH ProbesNoNo
16FP89716Sixteen Additional FISH ProbesNoNo
17FP89717Seventeen Additional FISH ProbesNoNo
18FP89718Eighteen Additional FISH ProbesNoNo
19FP89719Nineteen Additional FISH ProbesNoNo
20FP89720Twenty Additional FISH ProbesNoNo

Testing Algorithm Delineates situation(s) when tests are added to the initial order. This includes reflex and additional tests.

FISH testing is recommended in place of chromosome analysis for this disorder. This panel includes testing for the following anomalies via the probes listed:

 

 6q-, MYB/Cen6

11q-, ATM/Cen11

+12, D12Z3/MDM2

13q-, D13S319/LAMP1

17p-, TP53/Cen17

t(11;14), CCND1/IGH

Reflex for IGH anomaly:

t(14;18), IGH/BCL2

t(14;18), IGH/BCL3

 

If the patient is being tracked for known anomalies, please indicate which anomalies need to be investigated.

 

When this test is ordered 12 FISH probes are included. If further probes beyond the initial 12 are needed, they will be added at an additional charge.

Special Instructions and Forms Describes specimen collection and preparation information, test algorithms, and other information pertinent to test. Also includes pertinent information and consent forms to be used when requesting a particular test

Method Name A short description of the method used to perform the test

Fluorescence In Situ Hybridization (FISH)

Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name

CLL, FISH

Aliases Lists additional common names for a test, as an aid in searching

+12
ATM
c-MYB
CCND1-XT
Chromosome Analysis by FISH Panel for Chronic Lymphocytic
Chronic Lymphocytic Leukemia (CLL)
CLL (Chronic Lymphocytic Leukemia)
Deletion 11q
Deletion 13q
Deletion 17p
Deletion 6p
FISH for Chronic Lymphocytic Leukemia
FISH for CLL (Chronic Lymphocytic Leukemia)
IGH
LAMP1
Leukemia CLL (Chronic Lymphocytic Leukemia)
p53
t(11:14)
MYB
TP53