HPFH - Overview: Hemoglobin F, Red Cell Distribution, Blood

Test Catalog

Test ID: HPFH    
Hemoglobin F, Red Cell Distribution, Blood

Useful For Suggests clinical disorders or settings where the test may be helpful

Distinguishing large deletional hereditary persistence of fetal hemoglobin from other conditions with increased percentage of fetal hemoglobin

Additional Tests Lists test(s) that are always performed, at an additional charge, with the initial test(s)

Test IDReporting NameAvailable SeparatelyAlways Performed
HBFHemoglobin F, BNoYes

Testing Algorithm Delineates situation(s) when tests are added to the initial order. This includes reflex and additional tests.

The percent of the patient’s hemoglobin F is very important to the clinical utility of this test. HBF / Hemoglobin F, Blood will be performed at an additional charge to determine if Hemoglobin F, Red Cell Distribution testing is warranted. If the hemoglobin F value from HBF / Hemoglobin F, Blood are normal for age or if value is <5% the HPFH / Hemoglobin F, Red Cell Distribution, Blood will not be performed. Samples with hemoglobin F (Hb F) levels >35% will be accepted but are discouraged due to decreased test specificity. For these markedly elevated Hb F levels, a hemoglobin electrophoresis profile with request for beta globin gene molecular testing for elevated Hb F levels is recommended.

Method Name A short description of the method used to perform the test

Flow Cytometry

NY State Approved Indicates the status of NY State approval and if the test is orderable for NY State clients.


Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name

Hemoglobin F, Red Cell Distrib, B

Aliases Lists additional common names for a test, as an aid in searching

Acid Elution Test for Fetal Hgb
Fetal Hemoglobin
Hemoglobin F, Red Cell Distribution, Blood - NOT FOR MATERNAL BLEED