82091 - Overview: Amyloid Protein Identification, Paraffin, LC-MS/MS

Test Catalog

Test Name

Test ID: 82091    
Amyloid Protein Identification, Paraffin, LC-MS/MS

Useful For Suggests clinical disorders or settings where the test may be helpful

Definitive identification of amyloid proteins

Reflex Tests Lists test(s) that may or may not be performed, at an additional charge, depending on the result and interpretation of the initial test(s)

Test IDReporting NameAvailable SeparatelyAlways Performed
62473AnatPath Consult, w/Slide PrepNoNo
62474AnatPath Consult, w/Comp Rvw of HisNoNo
61124HemePath Consult, w/Slide PrepNoNo
61125HemePath Consult, w/Comp Rvw of HisNoNo
62197RenalPath Consult, w/Slide PrepNoNo
62198RenalPath Consult, w/Comp Rvw of HisNoNo
89054Congo Red, StainNoNo
9901Puchtler's Mod Bennholds ST AmyloidNoNo

Testing Algorithm Delineates situation(s) when tests are added to the initial order. This includes reflex and additional tests.

In all cases with adequate tissue, an initial Congo red stain is performed before mass spectrometry testing to confirm positivity and pattern of amyloid deposition can be considered when interpreting mass spectrometry results. If initial Congo red stain is positive for amyloid, the 89054 / Congo Red, Stain will always be billed at an additional charge. If initial Congo red stain is negative for amyloid, the 82091 / Amyloid Protein Identification, Paraffin, LC-MS/MS will be cancelled and 9901 / Puchtler's Modification of Bennhold's Stain for Amyloid (Congo Red) will be charged. A pathology consultation is typically not required. If the amyloid subtyping results do not fit the clinical findings, a 70012 / Pathology Consultation may be added if appropriate, upon client approval.


See Laboratory Approach to the Diagnosis of Amyloidosis in Special Instructions

Special Instructions and Forms Describes specimen collection and preparation information, test algorithms, and other information pertinent to test. Also includes pertinent information and consent forms to be used when requesting a particular test

Method Name A short description of the method used to perform the test

82091: Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

89054 or 9901: Histological Stain

NY State Approved Indicates the status of NY State approval and if the test is orderable for NY State clients.


Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name

Amyloid Protein ID, Par, LC-MS/MS

Aliases Lists additional common names for a test, as an aid in searching

Amyloid AA
Amyloid AL
Amyloid ATTR
Amyloid LECT-2

The Amyloid Protein Identification test employs Liquid Tissue® sample preparation licensed from Expression Pathology Inc., Rockville MD, under U.S. Patent 7,473,532 and patents pending and foreign equivalents thereof.