Definitive identification of amyloid proteins
|Test ID||Reporting Name||Available Separately||Always Performed|
|62473||AnatPath Consult, w/Slide Prep||No||No|
|62474||AnatPath Consult, w/Comp Rvw of His||No||No|
|61124||HemePath Consult, w/Slide Prep||No||No|
|61125||HemePath Consult, w/Comp Rvw of His||No||No|
|62197||RenalPath Consult, w/Slide Prep||No||No|
|62198||RenalPath Consult, w/Comp Rvw of His||No||No|
|89054||Congo Red, Stain||No||No|
|9901||Puchtler's Mod Bennholds ST Amyloid||No||No|
In all cases with adequate tissue, an initial Congo red stain is performed before mass spectrometry testing to confirm positivity and pattern of amyloid deposition can be considered when interpreting mass spectrometry results. If initial Congo red stain is positive for amyloid, the 89054 / Congo Red, Stain will always be billed at an additional charge. If initial Congo red stain is negative for amyloid, the 82091 / Amyloid Protein Identification, Paraffin, LC-MS/MS will be cancelled and 9901 / Puchtler's Modification of Bennhold's Stain for Amyloid (Congo Red) will be charged. A pathology consultation is typically not required. If the amyloid subtyping results do not fit the clinical findings, a 70012 / Pathology Consultation may be added if appropriate, upon client approval.
82091: Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
89054 or 9901: Histological Stain
Amyloid Protein ID, Par, LC-MS/MS
The Amyloid Protein Identification test employs Liquid Tissue® sample preparation licensed from Expression Pathology Inc., Rockville MD, under U.S. Patent 7,473,532 and patents pending and foreign equivalents thereof.