Test ID: HBELC
Hemoglobin Electrophoresis Cascade, Blood
Secondary ID
A test code used for billing and in test definitions created prior to November 2011
NY State Approved
Indicates the status of NY State approval and if the test is orderable for NY State clients.
Useful For
Suggests clinical disorders or settings where the test may be helpful
Diagnosis of thalassemias and hemoglobin variants
Evaluation of unexplained microcytosis
Profile Information
A profile is a group of laboratory tests that are ordered and performed together under a single Mayo Test ID. Profile information lists the test performed, inclusive of the test fee, when a profile is ordered and includes reporting names and individual availability.
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| A2F | Hemoglobin A2 and F | Yes | Yes |
| HBEL | Hemoglobin Electrophoresis, B | No | Yes |
Reflex Tests
Lists test(s) that may or may not be performed, at an additional charge, depending on the result and interpretation of the initial test(s)
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| HPFH | Hemoglobin F, Red Cell Distrib, B | Yes | No |
| UNHB | Hemoglobin, Unstable, B | Yes | No |
| SDEX | Hemoglobin S, Scrn, B | Yes | No |
| IEF | IEF Confirms | No | No |
| MASS | Hb Variant by Mass Spec, B | No | No |
| HGBMO | HGB Electrophoresis, Molecular | No | No |
Testing Algorithm
Delineates situation(s) when tests are added to the initial order. This includes reflex and additional tests.
Hemoglobin electrophoresis cascade will always include hemoglobin A(2) and F and hemoglobin electrophoresis.
Reflex testing-Hemoglobin electrophoresis reflex testing performed at additional charge, may include any or all of the following as indicated to identify rare hemoglobin variants present: hemoglobin S screen, unstable hemoglobin, IEF confirms, hemoglobin variant by mass spec, hemoglobin F red cell distribution, beta-globin gene, large del/dup, alpha-globin gene sequencing, and beta-globin gene sequencing.
Special Instructions and Forms
Describes specimen collection and preparation information, test algorithms, and other information pertinent to test. Also includes pertinent information and consent forms to be used when requesting a particular test
Method Name
A short description of the method used to perform the test
A2F/83341: Cation Exchange/High-Performance Liquid Chromatography (HPLC)
HBEL/81428: Capillary Electrophoresis
SDEX/9180: Hemoglobin S Solubility
UNHB/9095: Isopropanol Stability
IEF/81644: Isoelectric Focusing
HPFH/8270: Flow Cytometry
MASS/60286: Mass Spectrometry (MS)
HGBMO/29374: Polymerase Chain Reaction (PCR) Analysis/Multiplex Ligation-Dependent Probe Amplification (MLPA), Polymerase Chain Reaction (PCR)/DNA Sequencing
(PCR is utilized pursuant to a license agreement with Roche Molecular Systems, Inc.)
Reporting Name
A shorter/abbreviated version of the Published Name for a test; an abbreviated test name
Aliases
Lists additional common names for a test, as an aid in searching
Alpha Globin Variant
Barts Hemoglobin
Beta Globin Variant
Beta-Thalassemia
Fetal Hemoglobin
fetaldex (Hemoglobin F)
Hemoglobin A2
Hemoglobin Cascade
Hemoglobin Electrophoresis Cascade Level 1
Hemoglobin F
Hemoglobin Mass Spec Studies
Hemoglobin Molecular studies
Hemoglobin S, quant
Hemoglobin Variant
Hemoglobin-H Disease
HGB (Hemoglobin) Electrophoresis
Isoelectric Focusing
Sickling Test


