Search our Test Catalog. Specify what to search (name, test code, titles, everywhere) and how to search (begins with, contains)

Unit Code 81616:
B-Cell Acute Lymphoblastic Leukemia (ALL), FISH

Print Friendly View
Print Page Email Page

Useful For

As an adjunct to conventional chromosome studies in patients with

ALL, especially:

- When conventional chromosome studies do not demonstrate a

  classic chromosome anomaly

- For pediatric patients

- When results for conventional chromosome studies are normal

  or unavailable because of an unsuccessful study

 

Detecting clones with t(1;19), t(9;22), t(12;21), t(11;var), del(9p), 4,

10, or 17

 

Quantifying disease before treatment and after therapy for patients

with ALL

 

Assessing residual disease after treatment. In this situation, it is cost

effective to order only those FISH probes that produced abnormal

results prior to treatment.

Reflex Tests

 Unit Code  Reporting Name  Available Separately  Always Performed 
80024 One Additional FISH Probe No No
80025 Two Additional FISH Probes No No
87825 Three Additional FISH Probes No No
80026 Four Additional FISH Probes No No
87826 Five Additional FISH Probes No No
87827 Six Additional FISH Probes No No
87828 Seven Additional FISH Probes No No
87829 Eight Additional FISH Probes No No
87830 Nine Additional FISH Probes No No
87831 Ten Additional FISH Probes No No
87832 Eleven Additional FISH Probes No No
87833 Twelve Additional FISH Probes No No

Testing Algorithm

This panel includes testing for the following anomalies via the probes

listed. The entire panel is recommended for pediatric patients.

 

t(9;22), BCR/ABL

t(12;21), TEL/AML1

t(1;19), PBX/TCF3

4, 10, 17, Cen4/10/17

t(11q23;var), MLL

del(9p), p16/Cen9

 

Pediatric patients: Please indicate if you would like the entire panel. This is

suggested for pediatric patients with new diagnosis. If the patient is being

tracked for known anomalies, please indicate  which anomalies need

to be investigated.

 

Adult patients: Only FISH for BCR/ABL and MLL are recommended in

adult patients with B-Cell ALL.

 

When this test is ordered, 2 FISH probes are included. If further probes

are needed, they will be added at an additional charge.

Special Instructions and Forms

• Cytogenetics Hematologic FISH Panel Patient Information Sheet 

Method Name

Fluorescence In Situ Hybridization (FISH) with DNA Probes

Reporting Name

ALL (B-Cell), FISH

Ordering Mnemonic

FBALL
FALL

Aliases

4, 10, 17

11q23 (MLL)

Acute Lymphoblastic Leukemia (ALL)

Adult Acute Lymphoblastic Leukemia (ALL)

Adult ALL (Acute Lymphoblastic Leukemia)

ALL (Acute Lymphoblastic Leukemia)

del(9p) (p16)

Hyperdiploidy

Pediatric Acute Lymphoblastic Leukemia (ALL)

Pediatric ALL (Acute Lymphoblastic Leukemia)

t(1;19) (PBX1/TCF3)

t(12;21) (TEL/AML1)

t(9;22) (BCR/ABL)

Key