|Values are valid only on day of printing.|
Diagnosis of mucopolysaccharidosis VI (Maroteaux-Lamy syndrome)
Diagnostic testing for mucopolysaccharidosis VI (Maroteaux-Lamy syndrome). Not recommended for carrier detection.
Arylsulfatase B deficiency results in mucopolysaccharidosis type VI (MPS VI), also called Maroteaux-Lamy syndrome.
Decreased or absent activity of arylsulfatase B in fibroblasts is diagnostic for MPS VI.
Arylsulfatase B activity may also be decreased in patients with multiple sulfatase deficiency and mucolipidosis II; however, the enzyme activity may not be as low as it is in patients with MPS VI.
This test is not indicated to determine carrier status for MPS VI.
|Test ID||Reporting Name||Available Separately||Always Performed|
|CRYOB||Cryopreserve for Biochem Studies||No||Yes|
When this test is ordered, a fibroblast culture and cryopreservation for biochemical studies will always be performed at an additional charge. However, for multiple lysosomal enzyme assays on a patient utilizing fibroblast culture, only 1 culture is required regardless of the number of enzyme assays ordered. If viable cells are not obtained within 10 days, client will be notified.
ARSB: Colorimetric Enzyme Assay
FIBR: Cultivated from Biopsy as Monolayer
CRYOB: Fibroblast Subculture Followed by Cryopreservation and Storage