Unit Code 81419:
Factor V Leiden (R506Q) Mutation, Blood
Useful For
Direct mutation analysis should be reserved for patients with
clinically suspected thrombophilia and:
-APC-resistance proven or suspected by a low APC-resistance ratio
-Family history of the FV Leiden mutation
Additionally, it may be appropriate to screen those women contemplating
oral contraceptive use or pregnancy, with consideration of an alternative
form of contraceptive therapy or VTE prophylaxis during pregnancy
and/or the post-partum state for women with FV Leiden allele.
Knowledge of the FV Leiden allele status may alter anticoagulation
management of VTE patients.
Special Instructions and Forms
Method Name
Direct Mutation Analysis
Reporting Name
Factor V Leiden (R506Q) Mutation, B
Ordering Mnemonic
F5DNA
Aliases
Activated protein C (APC) resistance mutation
APC resistance mutation
Factor V Leiden mutation
External
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