POXA - Overview: Oxalate, Plasma

Test Catalog

Test ID: POXA    
Oxalate, Plasma

Useful For Suggests clinical disorders or settings where the test may be helpful

Assessing the body pool size of oxalate. The settings in which it has been most useful include patients with enzyme deficiencies, such as primary hyperoxaluria, which result in overproduction of oxalate or patients with enteric hyperoxaluria (EH).

 

In the presence of chronic kidney disease (CKD), 3 uses of plasma oxalate are:

 

-If primary hyperoxaluria (PH) is suspected in a patient with CKD of indeterminate cause, and urinary oxalate is not available, plasma oxalate can be used to aid in diagnosis. However although  plasma oxalate levels are markedly elevated in PH patients with CKD suggesting the diagnosis, ancillary tests often are necessary to confirm it, such as genetic analysis of the 3 causative genes, or pathologic demonstration of oxalate crystals in tissues

-Monitoring patients with renal failure and primary or enteric hyperoxaluria in order to be sure they are receiving enough dialysis

-An aid in maintaining plasma oxalate levels below supersaturation (25-30 mcmol/L)

Testing Algorithm Delineates situation(s) when tests are added to the initial order. This includes reflex and additional tests.

See Hyperoxaluria Diagnostic Algorithm in Special Instructions.

Special Instructions and Forms Describes specimen collection and preparation information, test algorithms, and other information pertinent to test. Also includes pertinent information and consent forms to be used when requesting a particular test

Method Name A short description of the method used to perform the test

Ion Chromatography (IC)

NY State Approved Indicates the status of NY State approval and if the test is orderable for NY State clients.

Yes

Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name

Oxalate, P

Aliases Lists additional common names for a test, as an aid in searching

Oxalate