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Assessing the body pool size of oxalate. The settings in which it has been most useful include patients with enzyme deficiencies, such as primary hyperoxaluria, which result in overproduction of oxalate.
In the presence of renal insufficiency, 3 uses of plasma oxalate are:
-In those patients with renal insufficiency from indeterminate causes and in whom the question of primary hyperoxaluria has arisen and urinary oxalate is not available, plasma oxalate has been used for diagnosis of primary hyperoxaluria
-Monitoring patients with renal failure who are thought to have primary hyperoxaluria
-As an aid to maintaining plasma oxalate at levels below that which supersaturation occurs
See Hyperoxaluria Diagnostic Algorithm in Special Instructions.