Unit Code 81252:
Zygosity Testing (Multiple Births)
Useful For
Determining genetic risk for an individual whose twin/triplet
is affected with a genetic disorder for which a specific genetic
test is not available (or such testing is uninformative)
Assessment of risks prenatally when 1 fetus of multiples is known
to be affected by a specific disorder
Organ or bone marrow transplantation compatibility testing
Familial/parental interest
Reflex Tests
| Unit Code | Reporting Name | Available Separately | Always Performed |
| 80333 | Fibroblast Culture for Genetic Test | Yes | No |
| 80334 | Amniotic Fluid Culture/Genetic Test | Yes | No |
Testing Algorithm
If amniotic fluid (non-confluent cultured cells) is received, amniotic
fluid culture/genetic test will be added and charged separately. If
chorionic villus specimen (non-confluent cultured cells) is received,
fibroblast culture for genetic test will be added and charged separately.
Testing Guides and Forms
Method Name
Polymerase chain reaction (PCR)/microsatellite markers
are used to provide a genotype for multiples and their
parents to determine if siblings are monozygotic twins.
(PCR is utilized pursuant to a license agreement with
Roche Molecular Systems, Inc.)
Reporting Name
Zygosity Testing (Multiple Births)
Ordering Mnemonic
ZYG
Aliases
Identical Twins
Multiple Births
Triplets
Twins


