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Unit Code 80027:
B-Cell Lymphoma, FISH, Tissue

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Useful For

Detecting chromosome anomalies in paraffin-embedded lymphoid

tissue

 

Providing diagnostic and prognostic genetic information for the following

lymphomas:  mantle cell, follicular, Burkitt, and diffuse large B-cell

lymphoma

 

We recommend this test in cases where the diagnosis is questionable,

or potential prognostic information may become available

Reflex Tests

 Unit Code  Reporting Name  Available Separately  Always Performed 
80024 One Additional FISH Probe No No
80025 Two Additional FISH Probes No No
87825 Three Additional FISH Probes No No
80026 Four Additional FISH Probes No No
87826 Five Additional FISH Probes No No
87827 Six Additional FISH Probes No No
87828 Seven Additional FISH Probes No No
87829 Eight Additional FISH Probes No No
87830 Nine Additional FISH Probes No No
87831 Ten Additional FISH Probes No No
87832 Eleven Additional FISH Probes No No
87833 Twelve Additional FISH Probes No No

Testing Algorithm

This test includes a mini-pathology consultation to evaluate appropriate

FISH probes and translocations to investigate. Panel includes testing for

the following anomalies via the probes listed:

 

t(11;14), CCND1/IGH

t(14;18), IGH/BCL2

t(8q24.1:var), c-MYC

t(8:14), c-MYC/IGH

t(11;18), API2/MALT1

reflex t(14;18), IGH/MALT1

t(3q27;var), BCL6

Cen3/Cen7

Cen12/Cen18

 

If the patient is being tracked for known anomalies, please indicate which

anomalies need to be investigated.

 

When this test is ordered, 2 FISH probes are included. If further probes

are needed, they will be added at an additional charge.

Testing Guides and Forms

Method Name

Fluorescence In Situ Hybridization (FISH) with DNA Probes

Reporting Name

B-Cell Lymphoma, FISH, Ts

Ordering Mnemonic

PFLYM
FBLYM

Aliases

11;14 translocation

11;18 translocation

14;18 translocation

3q27 FISH

8;14 translocation

API2/MALT1

BCL1

BCL2/IGH

BCL6

c-MYC/IGH

CCND1/IGH

FISH for Burkitt lymphoma

FISH for Cyclin D1

FISH for diffuse large cell lymphoma

FISH for follicular lymphoma

FISH for mantle cell lymphoma

PRAD1

t(11;14)

t(11;18)

t(14;18)

t(8;14)


Key