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Test ID: PNEOE    
Paraneoplastic Autoantibody Evaluation, Spinal Fluid

Secondary ID A test code used for billing and in test definitions created prior to November 2011

80013

NY State Approved Indicates the status of NY State approval and if the test is orderable for NY State clients.

Yes

Useful For Suggests clinical disorders or settings where the test may be helpful

Aids in the diagnosis of paraneoplastic neurological autoimmune disorders related to carcinoma of lung, breast, ovary, thymoma, or Hodgkin lymphoma

Profile Information A profile is a group of laboratory tests that are ordered and performed together under a single Mayo Test ID. Profile information lists the test performed, inclusive of the test fee, when a profile is ordered and includes reporting names and individual availability.

Test IDReporting NameAvailable SeparatelyAlways Performed
ANN1CAnti-Neuronal Nuclear Ab, Type 1NoYes
ANN2CAnti-Neuronal Nuclear Ab, Type 2NoYes
ANN3CAnti-Neuronal Nuclear Ab, Type 3NoYes
AGN1CAnti-Glial Nuclear Ab, Type 1NoYes
PCA1CPurkinje Cell Cytoplasmic Ab Type 1NoYes
PCA2CPurkinje Cell Cytoplasmic Ab Type 2NoYes
PCTRCPurkinje Cell Cytoplasmc Ab Type TrNoYes
AMPHCAmphiphysin Ab, CSFNoYes
CRMCCRMP-5-IgG, CSFNoYes

Reflex Tests Lists test(s) that may or may not be performed, at an additional charge, depending on the result and interpretation of the initial test(s)

Test IDReporting NameAvailable SeparatelyAlways Performed
WBNCParaneoplas Autoantibody WBlot,CSFNoNo
CRMWCCRMP-5-IgG Western Blot, CSFNoNo
GD65CGAD65 Ab Assay, CSFYesNo
ABLTCAmphiphysin Western Blot, CSFNoNo
NMOCCNMO/AQP4-IgG CBA, CSFYesNo
NMDCCNMDA-R Ab CBA, CSFNoNo
AMPCCAMPA-R Ab CBA, CSFNoNo
GABCCGABA-B-R Ab CBA, CSFNoNo
NMDICNMDA-R Ab IF Titer Assay, CSFNoNo
AMPICAMPA-R Ab IF Titer Assay, CSFNoNo
GABICGABA-B-R Ab IF Titer Assay, CSFNoNo
VGKCCVGKC-complex Ab IPA, CSFNoNo

Testing Algorithm Delineates situation(s) when tests are added to the initial order. This includes reflex and additional tests.

If indirect immunofluorescence assay (IFA) (ANN1C, ANN2C, ANN3C, PCA1C, PCA2C, PCTRC, AMPHC, CRMC, AGN1C) is indeterminate, then paraneoplastic autoantibody Western blot is performed at an additional charge.

If IFA pattern suggest NMO/AQP4-IgG, then NMO/AQP4-IgG CBA is performed at an additional charge.

If client requests, or if IFA patterns suggest CRMP-5-IgG, then CRMP-5-IgG Western blot is performed at an additional charge.

If IFA patterns suggest GAD65 antibody, then GAD65 antibody radioimmunoassay is performed at an additional charge.

If IFA patterns suggest neuronal voltage-gated potassium channel-complex autoantibody, then VGKC-complex antibody IPA is performed at an additional charge.

If IFA patterns suggest amphiphysin antibody, then amphiphysin Western blot is performed at an additional charge.

If IFA pattern suggest NMDA-R, then NMDA-R antibody CBA and/or NMDA-R titer is performed at an additional charge.

If IFA pattern suggest AMPA-R, then AMPA-R antibody CBA and/or AMPA-R titer is performed at an additional charge.

If IFA pattern suggest GABA-B-R, then GABA-B-R antibody CBA and/or GABA-B-R titer is performed at an additional charge.

 

In patients with a history of tobacco use or other lung cancer risk, or if thymoma is suspected, PAVAL / Paraneoplastic Autoantibody Evaluation, Serum is also recommended.

 

See Paraneoplastic Autoantibody CSF Evaluation Algorithm in Special Instructions.

Special Instructions and Forms Describes specimen collection and preparation information, test algorithms, and other information pertinent to test. Also includes pertinent information and consent forms to be used when requesting a particular test

Method Name A short description of the method used to perform the test

ANN1C, ANN2C, ANN3C, PCA1C, PCA2C, PCTRC, AMPHC, CRMC, AGN1C, NMDIC, AMPIC, GABIC: Indirect Immunofluorescence Assay (IFA)

WBNC, CRMWC, ABLTC: Western Blot

GD65C, VGKCC: Radioimmunoassay

NMOCC, NMDCC, AMPCC, GABCC: Cell-Binding Assay (CBA)

Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name

Paraneoplas Autoantibody Eval,CSF

Aliases Lists additional common names for a test, as an aid in searching

Anti-Hu
Antineuronal
Cerebellar Antibodies
Dorsal Root Ganglion Antibody
Hu Antibody
Neuron Restricted Autoantibodies
Neuronal Nuclear Antibody
Neuronal-Anti
Ovarian Cancer-Related Antibodies
Paraneoplastic Autoantibody Western Blot Confirmation, CSF
Paraneoplastic Neurological Autoimmunity
Purkinje Cell Cytoplasmic Antibodies
Ri, Anti
Yo-Anti
Amphiphysin Ab, CSF (order PNEOE)
ANNA-1, CSF (order PNEOE)
ANNA-2, CSF (order PNEOE)
ANNA-3, CSF (order PNEOE)
CRMP-5-IgG, CSF (order PNEOE)
PCA-1, CSF (order PNEOE)
PCA-2, CSF (order PNEOE)
PCA-Tr, CSF (order PNEOE)