70016 - Overview: Hematopathology Consultation, Wet Tissue

Test Catalog

Test Name

Test ID: 70016    
Hematopathology Consultation, Wet Tissue

Useful For Suggests clinical disorders or settings where the test may be helpful

Obtaining a rapid, expert opinion on unprocessed specimens referred by the primary pathologist


Obtaining special studies not available locally

Reflex Tests Lists test(s) that may or may not be performed, at an additional charge, depending on the result and interpretation of the initial test(s)

Test IDReporting NameAvailable SeparatelyAlways Performed
82972Peripheral Blood Smear ExaminationNoNo
9172Bone Marrow BxNoNo
9196Bone Marrow AspirateNoNo
61648HemePath, Level I, Gross ExamNoNo
61649HemePath, Level II, Wet TissueNoNo
61661HemePath, Level III, Wet TissueNoNo
61662HemePath, Level IV, Wet TissueNoNo
61663HemePath, Level V, Wet TissueNoNo
61664HemePath, Level VI, Wet TissueNoNo
61123HemePath Consult, Outside SlideNo, (Bill Only)No
61124HemePath Consult, w/Slide PrepNo, (Bill Only)No
62373HemePath Consult, w/USS ProfNo, (Bill Only)No
61125HemePath Consult, w/Comp Rvw of HisNo, (Bill Only)No

Testing Algorithm Delineates situation(s) when tests are added to the initial order. This includes reflex and additional tests.

A Mayo Clinic hematopathologist will provide a full bone marrow workup which includes an evaluation of the specimen and determination of a diagnosis provided within a formal pathology report.

When a consultation is requested, the client is responsible for submitting the following specimens:

1. Wet (fresh) core biopsy and/or bone marrow aspirate clot submitted in formalin

2. Bone marrow aspirate samples collected in:

a. Lavender top (EDTA): molecular testing

b. Yellow top (ACD): flow cytometric testing

c. Green top (sodium heparin): chromosome analysis and FISH testing

3. Slides prepared from bone marrow and peripheral blood


Ancillary Testing

Based on Mayo Clinic-approved algorithms and/or a staff hematopathologists' discretion, ancillary testing may be performed in order to render an accurate diagnosis and provide important prognostic information. These test results will be incorporated into the consultative report and will be billed and reported separately.


-Tier 1 Testing: eg, cytochemical stains on bone marrow aspirate smear, immunohistochemical stains on bone marrow biopsy or clot sections, chromosome analysis, FISH, flow cytometry and/or molecular testing will be added as appropriate. Results will be incorporated into the pathology report, as well as, some separate standalone results may be released. All will be charged.

-Tier 2 Testing: eg, Next Generation Sequencing (NGS) or microarray testing will only be added upon approval of the ordering physician/pathologist (client).


If ancillary testing (eg, flow cytometry) is desired by the client outside of this consultation, each test must be ordered separately. Tests ordered outside of the consultation may or may not be integrated into the final pathology report based on staff hematopathologist's discretion.


If the volume of bone marrow aspirate is limited, prioritization of testing will be determined by the staff hematopathologist. Testing requested/suggested by the referring physician (immunostains, molecular studies, etc) may not be performed if deemed unnecessary by the reviewing staff hematopathologist.


Note: Calls are not routinely made; however, depending on the nature of the case, a call may be placed to the ordering provider or pathologist. These situations include, but are not limited to, a new diagnosis of acute leukemia or aggressive high grade lymphoma. To contact a Mayo Clinic Hematopathologist, please call the Hematopathology Communications team, 507-284-5600.


If a client chooses to embed the clot/biopsy, the bone marrow aspirate specimens (tubes) should be sent in the same package as the bone marrow biopsy/clot sections. Embedding at the client site may delay specimen arrival at Mayo Medical Laboratories and preclude the ability to perform some ancillary testing due to specimen stability.


If a consultation is requested and only formalin-fixed, paraffin-embedded (FFPE) samples will be submitted, please order 70012 / Pathology Consultation.

Special Instructions and Forms Describes specimen collection and preparation information, test algorithms, and other information pertinent to test. Also includes pertinent information and consent forms to be used when requesting a particular test

NY State Approved Indicates the status of NY State approval and if the test is orderable for NY State clients.


Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name

HemePath Consultation, Wet Tissue

Aliases Lists additional common names for a test, as an aid in searching

Acute leukemia consultation
Acute lymphocytic leukemia-differentiate T from non-T cell forms
Bone Marrow Consultation
Hematology Consultation, Slides or Blocks
Surgical Pathology Consultation, Slides or Blocks
Pathology Consultation