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Test ID: 62512    
Small Lymphocytic Lymphoma, FISH, Tissue

NY State Approved Indicates the status of NY State approval and if the test is orderable for NY State clients.

Conditional

Useful For Suggests clinical disorders or settings where the test may be helpful

Detecting a neoplastic clone associated with the common chromosome abnormalities seen in patients with small lymphocytic lymphoma (SLL) and other low-grade B-cell lymphomas.

 

Distinguishing patients with 11;14 translocations who have mantle cell lymphoma from patients who have SLL.

Reflex Tests Lists test(s) that may or may not be performed, at an additional charge, depending on the result and interpretation of the initial test(s)

Test IDReporting NameAvailable SeparatelyAlways Performed
19169One Additional FISH ProbeNo, (Bill Only)No
19170Two Additional FISH ProbesNo, (Bill Only)No
19432Three Additional FISH ProbesNo, (Bill Only)No
19171Four Additional FISH ProbesNo, (Bill Only)No
19433Five Additional FISH ProbesNo, (Bill Only)No
19434Six Additional FISH ProbesNo, (Bill Only)No
19435Seven Additional FISH ProbesNo, (Bill Only)No
19436Eight Additional FISH ProbesNo, (Bill Only)No
19437Nine Additional FISH ProbesNo, (Bill Only)No
19438Ten Additional FISH ProbesNo, (Bill Only)No
19439Eleven Additional FISH ProbesNo, (Bill Only)No
19440Twelve Additional FISH ProbesNo, (Bill Only)No
19855Thirteen Additional FISH ProbesNo, (Bill Only)No
19856Fourteen Additional FISH ProbesNo, (Bill Only)No
19857Fifteen Additional FISH ProbesNo, (Bill Only)No
19858Sixteen Additional FISH ProbesNo, (Bill Only)No
19859Seventeen Additional FISH ProbesNo, (Bill Only)No
19860Eighteen Additional FISH ProbesNo, (Bill Only)No
19861Nineteen Additional FISH ProbesNo, (Bill Only)No
19862Twenty Additional FISH ProbesNo, (Bill Only)No

Testing Algorithm Delineates situation(s) when tests are added to the initial order. This includes reflex and additional tests.

This test does not include a pathology consult. If a pathology consult is requested, 70012 / Pathology Consultation should be ordered and the appropriate FISH test will be ordered and performed at an additional charge.

The number of probes ordered will determine the price of the testing. When this test is ordered, a charge for 2 FISH probes and interpretation is included. If additional probes or the entire panel are ordered, they will be performed at an additional charge.  

Panel includes testing for the following anomalies via the probes listed:

6q-, D6Z1/MYB

11q-, D11Z1/ATM

+12, D12Z3/MDM2

13q-, D13S319/LAMP1

17p-, TP53/D17Z1

t(11;14), CCND1-XT/IGH-XT

Reflex for IGH Abnormality:

t(14;18), IGH/BCL2

t(14;19), IGH/BCL3

-When 3 copies of IGH are observed with no fusion to CCND1, reflex testing using the IGH/BCL2 and IGH/BCL3 probe sets are performed to identify a potential t(14;18)(q32;q21) or t(14;19)(q32;q13) rearrangement.

Method Name A short description of the method used to perform the test

Fluorescence In Situ Hybridization (FISH)

Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name

SLL, FISH, Ts