Evaluating chronic lymphocytic leukemia patients at diagnosis or during disease course for the presence of TP53 gene mutations indicating high risk of disease progression and adverse outcome
|Test ID||Reporting Name||Available Separately||Always Performed|
|CKP53||CKP53 Protocol, B||No||No|
Flow cytometry CKP53 / CKP53 Protocol, Blood may be performed on peripheral blood samples to verify diagnosis of chronic lymphocytic leukemia (CLL) and determine the percent B-cells in the sample prior to TP53 testing. See TP53 Sequencing Testing Algorithm in Special Instructions.
Polymerase Chain Reaction (PCR) and Sanger Sequencing
(PCR is utilized pursuant to a license agreement with Roche Molecular Systems, Inc.)
TP53 gene somatic mutation analysis