OLIWB - Overview: Oligosaccharidoses Screen, Leukocytes

Test Catalog

Test ID: OLIWB    
Oligosaccharidoses Screen, Leukocytes

Useful For Suggests clinical disorders or settings where the test may be helpful

Screening for a subset of oligosaccharidoses in leukocytes

Genetics Test Information Provides information that may help with selection of the correct test or proper submission of the test request

This is a screening method for several oligosaccharidoses. Additional biochemical or molecular genetic testing is required to confirm abnormal results.

Highlights

The oligosaccharide screening test analyzes the activity of 4 enzymes in leukocytes via tandem mass spectrometry.

 

Deficiency or absence of these enzymes is associated with 5 different oligosaccharidoses, including alpha-mannosidosis, beta-mannosidosis, alpha-fucosidosis, GM1 gangliosidosis, and Morquio B.

 

Patients with mild clinical phenotypes may not be detected by this test.

Special Instructions and Forms Describes specimen collection and preparation information, test algorithms, and other information pertinent to test. Also includes pertinent information and consent forms to be used when requesting a particular test

Method Name A short description of the method used to perform the test

Enzyme Reaction Assay Followed by Flow Injection Analysis-Tandem Mass Spectrometry (FIA-MS/MS)

NY State Approved Indicates the status of NY State approval and if the test is orderable for NY State clients.

Conditional

Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name

Oligosaccharidoses Screen, WBC

Aliases Lists additional common names for a test, as an aid in searching

Alpha-Fucosidosis
Alpha-Mannosidosis
Beta-Mannosidosis
GM1 Gangliosidosis
Morquio B