SLC1O - Overview: Solute Carrier Organic Anion Transporter Family Member 1B1 (SLCO1B1) Genotype, Statin, Saliva

Test Catalog

Test ID: SLC1O    
Solute Carrier Organic Anion Transporter Family Member 1B1 (SLCO1B1) Genotype, Statin, Saliva

Useful For Suggests clinical disorders or settings where the test may be helpful

Aiding risk prediction of statin-associated myopathy for patients beginning statin therapy, especially simvastatin therapy

 

Determining a potential genetic effect related to statin intolerance in patients with statin-associated myopathy, especially related to simvastatin

 

Genotyping patients who prefer not to have venipuncture done

Genetics Test Information Provides information that may help with selection of the correct test or proper submission of the test request

This is a pharmacogenomics test for the SLCO1B1*5 (c.521T>C, p.V174A; rs4149056) allele. Presence of the *5 allele is associated with an increased risk for simvastatin-associated myopathy.

Testing Algorithm Delineates situation(s) when tests are added to the initial order. This includes reflex and additional tests.

 

Special Instructions and Forms Describes specimen collection and preparation information, test algorithms, and other information pertinent to test. Also includes pertinent information and consent forms to be used when requesting a particular test

Method Name A short description of the method used to perform the test

Polymerase Chain Reaction (PCR) 5’-Nuclease End-Point Allelic Discrimination Analysis

(PCR is utilized pursuant to a license agreement with Roche Molecular Systems, Inc.)

NY State Approved Indicates the status of NY State approval and if the test is orderable for NY State clients.

Conditional

Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name

SLCO1B1 Genotype, Statin, Saliva

Aliases Lists additional common names for a test, as an aid in searching

SLCO1B1
OATP1B1