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Test ID: FPLAS    
Plasma Cell Proliferative Disorder, FISH, Tissue

Available on the App Store

NY State Approved Indicates the status of NY State approval and if the test is orderable for NY State clients.

Yes

Useful For Suggests clinical disorders or settings where the test may be helpful

Supporting the diagnosis of plasmacytoma when coordinated with a surgical pathology consultation 

Reflex Tests Lists test(s) that may or may not be performed, at an additional charge, depending on the result and interpretation of the initial test(s)

Test IDReporting NameAvailable SeparatelyAlways Performed
ADD1FOne Additional FISH ProbeNoNo
ADD2FTwo Additional FISH ProbesNoNo
ADD3FThree Additional FISH ProbesNoNo
ADD4FFour Additional FISH ProbesNoNo
ADD5FFive Additional FISH ProbesNoNo
ADD6FSix Additional FISH ProbesNoNo
ADD7FSeven Additional FISH ProbesNoNo
ADD8FEight Additional FISH ProbesNoNo
ADD9FNine Additional FISH ProbesNoNo
ADD10Ten Additional FISH ProbesNoNo
ADD11Eleven Additional FISH ProbesNoNo
ADD12Twelve Additional FISH ProbesNoNo
13FPThirteen Additional FISH ProbesNoNo
14FPFourteen Additional FISH ProbesNoNo
15FPFifteen Additional FISH ProbesNoNo
16FPSixteen Additional FISH ProbesNoNo
17FPSeventeen Additional FISH ProbesNoNo
18FPEighteen Additional FISH ProbesNoNo
19FPNineteen Additional FISH ProbesNoNo
20FPTwenty Additional FISH ProbesNoNo
21FPTwenty One Additional FISH ProbesNoNo
22FPTwenty Two Additional FISH ProbesNoNo
23FPTwenty Three Additional FISH ProbesNoNo
24FPTwenty Four Additional FISH ProbesNoNo
25FPTwenty Five Additional FISH ProbesNoNo
26FPTwenty Six Additional FISH ProbesNoNo
27FPTwenty Seven Additional FISH ProbesNoNo
28FPTwenty Eight Additional FISH ProbesNoNo
29FPTwenty Nine Additional FISH ProbesNoNo
30FPThirty Additional FISH ProbesNoNo

Testing Algorithm Delineates situation(s) when tests are added to the initial order. This includes reflex and additional tests.

This test does not include a pathology consult. If a pathology consult is requested, order 70012 / Pathology Consultation and the appropriate FISH test will be ordered and performed at an additional charge.

 

The number of probes ordered will determine the price of the testing. When this test is ordered, a charge for 2 FISH probes and interpretation is included. If additional probes or the entire panel are ordered, additional probe charges will be added.

 

This test is designed for diagnostic specimens. The test panel includes analysis for the disease-associated abnormalities using the probes listed below:

 

-13/13q-, RB1/LAMP1

t(11;14), CCND1/IGH

t(14;var), IGH

17p-, TP53/Cen17

+3/+7, Cen3/Cen7

+9/+15, Cen9/Cen15

1q gain, TP73/CKS1B

t(8;var), MYC

 

When an IGH rearrangement is identified, reflex testing is performed to identify the translocation partner. Probes include identification of t(4;14)(p16.3;q32) FGFR3/IGH, t(14;16)(q32;q23) IGH/MAF, t(14;20)(q32;q12) IGH/MAFB, or t(6;14)(p21;q32) CCND3/IGH.

Method Name A short description of the method used to perform the test

Fluorescence In Situ Hybridization (FISH)

Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name

Plasma Cell Prolif, FISH, Ts

Aliases Lists additional common names for a test, as an aid in searching

+3/+7
+9/+15
13q-
-13
17p-
del(13q)
Deletion 13
Deletion 17p
Extramedullary plasmacytoma (EP)
Monosomy 13
Multiple Myeloma
Rb1
Solitary plasmacytoma of bone (SPB)
t(11;14) - CCND1/IGH
t(14;16) - IGH/c-MAF
t(14;20) - IGH/MAFB
t(4;14) - FGFR3/IGH
t(6;14) - CCND3/IGH
TP53
+1q
CKS1B
MYC