Test ID: SEQU
Sequential Maternal Screening, Part 1, Serum
Secondary ID 
A test code used for billing and in test definitions created prior to November 2011
NY State Approved Indicates the status of NY State approval and if the test is orderable for NY State clients.
Useful For Suggests clinical disorders or settings where the test may be helpful
Prenatal screening for Down syndrome:
-Part 1 (first trimester): nuchal translucency (NT), pregnancy-associated plasma protein A (PAPP-A)
-Part 2 (second trimester): alpha-fetoprotein (AFP), unconjugated estriol (uE3), human chorionic gonadotropin (hCG), and inhibin A
Prenatal screening for trisomy 18:
-Part 1 (first trimester): NT, PAPP-A
-Part 2 (second trimester): AFP, hCG, uE3
Prenatal screening for open neural tube defects:
-Part 2 (second trimester): AFP
Testing Algorithm Delineates situation(s) when tests are added to the initial order. This includes reflex and additional tests.
Sequential maternal screening is a 2-part test, with first- and second-trimester components. It requires a nuchal translucency (NT) measurement and blood draw in the first trimester. If the result from Part 1 indicates a risk for Down syndrome that is higher than the screen cutoff, the screen is completed and a report is issued. If Part 1 results are negative, an additional blood draw in the second trimester is required (see SEQF/60700 Sequential Maternal Screen, Part 2, Serum). If the second specimen is not received for sequential screening, the results are uninterpretable and no maternal risk will be provided.
See Sequential Maternal Serum Screening Algorithm in Special Instructions.
Special Instructions and Forms Describes specimen collection and preparation information, test algorithms, and other information pertinent to test. Also includes pertinent information and consent forms to be used when requesting a particular test
Method Name A short description of the method used to perform the test
Two-Site Immunoenzymatic (Sandwich) Assay
Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name
Aliases Lists additional common names for a test, as an aid in searching
Sequential Screening
Serum Stepwise Sequential Screen
Stepwise Maternal Screen
Stepwise Sequential
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