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Test ID: WARFO    
Warfarin Sensitivity Genotype by Sequence Analysis, Saliva

NY State Approved Indicates the status of NY State approval and if the test is orderable for NY State clients.


Useful For Suggests clinical disorders or settings where the test may be helpful

Assessing CYP2C9 and VKORC1 genes for polymorphisms affecting the metabolism of warfarin/Coumadin


Identifying patients who may require warfarin dosing adjustments(2,3) including:

-Patients who have previously been prescribed warfarin and have required multiple dosing adjustments to maintain the international normalized ratio in the target range

-Patients with a history of thrombosis or bleeding when previously taking warfarin

-Patients being started on a first prescription for warfarin


Genotyping patients who prefer not to have venipuncture done

Profile Information A profile is a group of laboratory tests that are ordered and performed together under a single Mayo Test ID. Profile information lists the test performed, inclusive of the test fee, when a profile is ordered and includes reporting names and individual availability.

Test IDReporting NameAvailable SeparatelyAlways Performed
WARSOWarfarin Sensitivity Genotype, SalivaNoYes
WARFQWarfarin Sensitivity GenotypingNoYes

Testing Algorithm Delineates situation(s) when tests are added to the initial order. This includes reflex and additional tests.


Special Instructions and Forms Describes specimen collection and preparation information, test algorithms, and other information pertinent to test. Also includes pertinent information and consent forms to be used when requesting a particular test

Method Name A short description of the method used to perform the test

Polymerase Chain Reaction (PCR) Followed by DNA Sequence Analysis

Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name

Warfarin Sensitive Genotype, Saliva

Aliases Lists additional common names for a test, as an aid in searching

Coumadin Genotype
Cytochrome P450 2C9 Genotyping
P450 2C9 Genotyping
Vitamin K Epoxide Reductase Subunit 1
Vitamin K Genotype (VKORC1)
VKORC1 (Vitamin K Genotype)
VKORC1 and 2C9
Warfarin Genotype
Warfarin Sensitivity