VMAR - Overview: Vanillylmandelic Acid (VMA), Random, Urine

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Test ID: VMAR    
Vanillylmandelic Acid (VMA), Random, Urine

Useful For Suggests clinical disorders or settings where the test may be helpful

Screening children for catecholamine-secreting tumors with a random urine collection when requesting vanillylmandelic acid only


Supporting a diagnosis of neuroblastoma


Monitoring patients with a treated neuroblastoma


Vanillylmandelic acid (VMA) and other catecholamine metabolites such as homovanillic acid (HVA) measurement in urine are used for screening children for catecholamine-secreting tumors such as neuroblastoma and other neural crest tumors and monitoring those who have had treatment for these tumors.


More than 90% of individuals with neuroblastoma have elevated VMA or HVA.


VMA is not the analyte of choice for diagnosis of pheochromocytoma, which is better detected by testing for metanephrines.


Treatment with L-dopa can impact test results and should be discontinued 24 hours prior to collection. Bactrim can impact test results and should be noted at time of collection.

Method Name A short description of the method used to perform the test

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

NY State Approved Indicates the status of NY State approval and if the test is orderable for NY State clients.


Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name

Vanillylmandelic Acid, Random, U

Aliases Lists additional common names for a test, as an aid in searching

3-Methoxy-4-Hydroxymandelic Acid
4-Hydroxy-3-Methoxymandelic Acid
Neuroblastoma Profile
Vanillylmandelic Acid