Test ID: HLLFH
Hematologic Disorders, Leukemia/Lymphoma; Flow Hold Varies
NY State Approved 
Indicates the status of NY State approval and if the test is orderable for NY State clients.
Useful For Suggests clinical disorders or settings where the test may be helpful
Evaluating lymphocytoses of undetermined etiology
Identifying B- and T-cell lymphoproliferative disorders involving blood and bone marrow
Distinguishing acute lymphoblastic leukemia (ALL) from acute myeloid leukemia (AML)
Immunologic subtyping of ALL
Distinguishing reactive lymphocytes and lymphoid hyperplasia from malignant lymphoma
Distinguishing between malignant lymphoma and acute leukemia
Phenotypic subclassification of B- and T-cell chronic lymphoproliferative disorders, including chronic lymphocytic leukemia, mantle cell lymphoma, and hairy cell leukemia
Recognizing AML with minimal morphologic or cytochemical evidence of differentiation
Recognizing monoclonal plasma cells
Reflex Tests Lists test(s) that may or may not be performed, at an additional charge, depending on the result and interpretation of the initial test(s)
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| 88465 | Flow Cytometry Interp, 2-8 Markers | No, (Bill Only) | No |
| 88466 | Flow Cytometry Interp, 9-15 Markers | No, (Bill Only) | No |
| 88467 | Flow Cytometry Interp,16 or greater | No, (Bill Only) | No |
Testing Algorithm Delineates situation(s) when tests are added to the initial order. This includes reflex and additional tests.
This test is designed to delay the start of leukemia/lymphoma immunophenotyping until the preliminary assessment is completed. Specimen are held in lab until noon (12 p.m. CST) 2 days after the collection date. For testing to be cancelled, the client must call Mayo Medical Laboratories at 800-533-1710. The testing process will be initiated and fully charged if no notification is received within this time period. To expedite the beginning testing, please call Mayo Medical Laboratories at 800-533-1710.
The testing process begins with a screening panel. The screening panel will be charged based on number of markers tested (80997 Flow Cytometry, Cell Surface, First for first marker, 81047 Flow Cytometry, Cell Surface, Additional for each additional marker). In addition, reflex testing may occur to fully characterize a disease state or clarify any abnormalities from the screening test. Reflex tests will be performed at an additional charge for each marker tested (80997 Flow Cytometry, Cell Surface, First if applicable, 81047 Flow Cytometry, Cell Surface, Additional, if applicable).
This limited panel, together with the provided clinical history and morphologic review, is used to determine what, if any, further testing is needed for disease diagnosis or classification. If additional testing is required, it will be added per algorithm to fully characterize a disease state with a charge per unique antibody tested.
Note: FISH or Molecular testing may be recommended by the Mayo pathologist in some cases. They will contact the referring physician or pathologist to confirm the addition of these tests.
Special Instructions and Forms Describes specimen collection and preparation information, test algorithms, and other information pertinent to test. Also includes pertinent information and consent forms to be used when requesting a particular test
Method Name A short description of the method used to perform the test
Flow Cytometry
Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name
Aliases Lists additional common names for a test, as an aid in searching
LLHOLD
LLHLD
Hold Immunophenotyping
Flow Hold
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