Test ID: HCASC
Hemochromatosis Cascade
NY State Approved 
Indicates the status of NY State approval and if the test is orderable for NY State clients.
Yes
Useful For Suggests clinical disorders or settings where the test may be helpful
Screening to identify those patients who may have or do have hereditary hemochromatosis and are at risk to develop clinical signs and symptoms of the disease
Genetics Test Information Provides information that may help with selection of the correct test or proper submission of the test request
If the ferritin value is abnormal (males >336 mcg/L; females >307 mcg/L) and other causes of an increased value are eliminated (liver disease, etc.), genetic testing for hereditary hemochromatosis (HHEMO/81508 Hemochromatosis HFE Gene Analysis, Blood) should be considered in adults.
Profile Information A profile is a group of laboratory tests that are ordered and performed together under a single Mayo Test ID. Profile information lists the test performed, inclusive of the test fee, when a profile is ordered and includes reporting names and individual availability.
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| HCFEC | FE-TIBC, S | Yes, (order FEC) | Yes |
| HCFER | Ferritin, S | Yes, (order FERR) | No |
Testing Algorithm Delineates situation(s) when tests are added to the initial order. This includes reflex and additional tests.
Transferrin saturation is performed first. If elevated (>45%), this will trigger determination of serum ferritin.
See Hereditary Hemochromatosis Algorithm in Special Instructions.
Special Instructions and Forms Describes specimen collection and preparation information, test algorithms, and other information pertinent to test. Also includes pertinent information and consent forms to be used when requesting a particular test
Method Name A short description of the method used to perform the test
HCFEC/34625: Photometric, Fe2+-FerroZine Complex
HCFER/23817: Immunoenzymatic Assay
Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name
Hemochromatosis Cascade
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