|Values are valid only on day of printing.|
Confirmation of a diagnosis of aminolevulinic acid dehydratase deficiency porphyria. Due to limited stability for this test, the preferred test for analysis of ALAD is ALAD / Aminolevulinic Acid Dehydratase (ALAD), Whole Blood.
This test will not detect lead intoxication.
Aminolevulinic acid dehydratase (ALAD) activity is inhibited in other situations including hereditary tyrosinemia type 1, lead intoxication, and exposure to styrene, trichloroethylene, or bromobenzene. These causes should be ruled out when considering a diagnosis of ALAD deficiency porphyria (ADP). This method will not exhibit a decreased ALAD enzyme activity due to lead intoxication. This test should only be ordered when the specimen will be received at Mayo Medical Laboratories within 24 hours of collection. The preferred test for analysis of ALAD is ALAD / Aminolevulinic Acid Dehydratase (ALAD), Whole Blood.
The following algorithms are available in Special Instructions:
-Porphyria (Acute) Testing Algorithm
-Porphyria (Cutaneous) Testing Algorithm
Enzymatic End point/Spectrofluorometric