NKCP - Overview: Natural Killer (NK) Cytotoxicity Profile

Test Catalog

Test ID: NKCP    
Natural Killer (NK) Cytotoxicity Profile

Useful For Suggests clinical disorders or settings where the test may be helpful

Natural Killer (NK) Cytotoxicity Profile:

-Assessment of patients with recurrent, severe herpes viral infections, primary or secondary hemophagocytic lymphohistiocytosis, and suspected or known monogenic defects affecting the NK cell compartment (approximately 30 known defects cause either functional or classic NK cell deficiency)

-Evaluation of immune reconstitution post hematopoietic cell transplantation and post immunomodulatory therapy


T- and B-Cell Quantitation by Flow Cytometry:

-Monitoring CD4 counts and assessing immune deficiencies

Profile Information A profile is a group of laboratory tests that are ordered and performed together under a single Mayo Test ID. Profile information lists the test performed, inclusive of the test fee, when a profile is ordered and includes reporting names and individual availability.

Test IDReporting NameAvailable SeparatelyAlways Performed
NKC1N.K. Cytotoxicity ResultNoYes
NKC2NKC Control TubeNoYes
TBBST- and B-Cell QN by Flow CytometryYesYes

Testing Algorithm Delineates situation(s) when tests are added to the initial order. This includes reflex and additional tests.

When multiple specimen types are required to perform a panel of tests, the laboratory will perform the entire panel only when the NKC portion is received within stability limits and the appropriate specimen. If only the NKC portion is received this test will still be performed. Be advised that this may change the degree of interpretation received with the report.

Method Name A short description of the method used to perform the test

NKC: (51) Cr Release Assay

TBBS: Flow Cytometry

NY State Approved Indicates the status of NY State approval and if the test is orderable for NY State clients.


Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name

N.K. Cytotoxicity Profile

Aliases Lists additional common names for a test, as an aid in searching

MHC Unrestricted Cytotoxicity Assay
Natrual Killer Cytotoxicity
NK Assay
NK Cytotoxicity
NK Function