|Values are valid only on day of printing.|
Evaluating patients suspected of having post cardiotomy or post myocardial infarction syndromes
Evaluating patients suspected of having inflammatory cardiomyopathy
Myocardial antibodies occur in the sera of patients who have acute rheumatic fever and carditis, or who have sustained mechanical (surgical or traumatic) or ischemic damage to myocardial tissue in the postcardiotomy and post myocardial infarction syndromes.
In the "myocardial injury" syndromes, circulating myocardial antibodies become detectable 2 to 3 weeks after the injury in 30% (infarction) to 70% (postsurgical) of cases and remain detectable for 3 to 8 weeks.
Myocardial antibodies have been detected in some patients with idiopathic cardiomyopathy.
The pathogenic significance of myocardial antibodies is not known.
If positive, results are titered.
Reference values apply to all ages.
Elevated in 30% of myocardial injury patients by the 2nd or 3rd week
No known false-positives or false-negatives
Twomey SL, Bernett GE: Immunofluorescence method for detecting anti-myocardial antibodies, and its use in diagnosing heart disease. Clin Chem 1975;21:1903-1906