FMYOP - Clinical: MyoMarker Panel 2

Test Catalog

Test ID: FMYOP    
MyoMarker Panel 2

Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test

1.  Anti-Jo 1 Abs are found in subset of myositis patients characterized by interstitial lung disease, systemic polyarthritis, Raynaud’s Phenomena, fever and Mechanic’s Hand (anti-synthetase syndrome).

2.  Anti-Jo 1 appears to be a marker for interstitial lung disease in polymyositis.

3. The anti-PM/Scl-100 antibody is associated with younger age, calcinosis and has lower rates of gastrointestinal symptoms, ILD and pulmonary hypertension. There is also evidence of a possibly better survival compared to the presence of either anti-PM/Scl-75 or anti-Scl-70 antibodies.

Reference Values Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.

Mi-2, PL-12, PL-7, EJ, OJ, SRP, Ku, U2 snRNP

 

Reference Range: Negative

 

Anti-PM/Scl-100 Ab, Anti-Jo-1 Ab

 

Reference Range: <20

 

EIA Interpretation:

 

Negative:                      <20 units

Weak Positive:              20 - 39 units

Moderate Positive:        40 - 80 units

Strong Positive:            >80 units

Tell Us What You Think