Circulating Immune Complexes (CIC)
Reference Values Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.
Negative <20 EU/mL
Borderline/Equivocal 20 – 25 EU/mL
Positive >25 EU/mL
Circulating immune complexes (CICs) are detectable in a variety of systemic disorders such as rheumatological, autoimmune, allergic diseases; viral, bacterial infections and malignancies. Although detection of CICs is neither essential nor specific for any disease, anti-C1q assay is likely to provide information regarding disease activity in lupus nephritis.